Topic: interhemispheric inhibition

Accumulating sensory information over long-time scales is a critical component of most circuit computations in the brain across species. It remains poorly understood how such dynamics are implemented mechanistically at the synaptic level. Dissecting such neural circuits in vertebrates requires precise knowledge of functional neural properties and correlating dynamics with the underlying wiring diagram within the same individual animal. Here we combine functional calcium imaging with ultrastructural circuit reconstruction, using a visual motion accumulation task in larval zebrafish. Using conne

Goal-directed movements are associated with unique neurophysiological alterations in motor-related brain regions. This study systematically examined the interhemispheric connectivity between the premotor (dorsal, PMd; ventral, PMv) and the primary motor (M1) cortices using dual-site transcranial magnetic stimulation. We had 30 right-handed young adults (15F; 26.5±4.3yrs) participate in three experimental conditions to examine interhemispheric inhibition (IHI) between: (1) PMd to M1, (2) PMv to M1 and (3) M1 to M1. PMd and PMv were located relative to M1 (PMd: 2cm anterior, 1cm medial; PMv: 3cm