Topic: Io

NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

PA-25-301, posted December 18, 2024 and currently open. NIH's parent announcement for investigator-initiated R01 research project grants not proposing clinical trials; standard NIH submission policies and due dates apply, with the listing closing January 7, 2028.

ISMB/ECCB 2027

The 35th ISMB conference joined with the 26th annual ECCB, hosted by the International Society for Computational Biology at the Bella Center Copenhagen and virtually - the year's most important computational biology event.

OHBM 2027 Annual Meeting

Annual meeting of the Organization for Human Brain Mapping at the Metro Toronto Convention Centre, bringing together researchers to share groundbreaking research, engage in educational forums, and foster collaboration across neuroimaging methods and applications.

ASM Microbe 2027

The American Society for Microbiology's annual gathering in Chicago, uniting three specialized meetings under one umbrella - the ASM Health Meeting, ASM Applied & Environmental Microbiology Meeting, and ASM Mechanism Discovery Meeting - with one registration granting full access.

ISSCR 2027 Annual Meeting

Annual meeting of the International Society for Stem Cell Research at the Moscone West Convention Center, San Francisco, recognizing 25 years of discovery, collaboration, and progress in stem cell science.

European Human Genetics Conference 2027

The 60th European Human Genetics Conference of the European Society of Human Genetics, held June 12-15, 2027 in Rotterdam, The Netherlands as a hybrid conference with in-person and virtual participation.

FENS Regional Meeting 2027

FENS Regional Meeting held 26-29 May 2027 in Istanbul, Turkey, jointly organised by the Neuroscience Society of Turkey, the Hellenic Society for Neuroscience, the Serbian Neuroscience Society and the Slovenian Neuroscience Association.

2027 IEEE International Conference on Robotics and Automation (ICRA)

The flagship conference of the IEEE Robotics and Automation Society, held May 24-28, 2027 at Coex in Seoul, South Korea, bringing together the world's top researchers and industry leaders to advance the field of robotics.

VSS 2027

The 2027 Annual Meeting of the Vision Sciences Society, held May 21-25, 2027 in Seattle, Washington, gathering the interdisciplinary vision science community spanning visual perception, psychophysics, and visual neuroscience.

APS Global Physics Summit 2027

The American Physical Society's Global Physics Summit, the world's largest annual physics research conference, joining the March Meeting and April Meeting; the 2027 edition is announced for April 11-16, 2027 in Atlanta, Georgia.

AACR Annual Meeting 2027

The American Association for Cancer Research's flagship annual meeting, themed 'Delivering Discovery Science: The Bridge to Breakthrough Therapeutics', at the Orange County Convention Center in Orlando, Florida.

ACS Spring 2027

One of the American Chemical Society's twice-yearly ACS Meetings & Expositions, held March 21-25, 2027 in New Orleans, LA, featuring presentations across the chemistry divisions and an exposition.

Cosyne 2027

The annual Computational and Systems Neuroscience (Cosyne) meeting, an exchange forum for experimental and theoretical/computational approaches to problems in systems neuroscience. Cosyne returns to Montreal, Canada, from 11-16 March 2027.

Cancer Neuroscience: Neural Mechanisms as Therapeutic Targets in Cancer

This Keystone Symposium examines how nerves and neural activity shape cancer initiation, progression, metastasis, cognition, and treatment, with a focus on actionable therapeutic targets.

Biophysical Society 71st Annual Meeting

The 71st Annual Meeting of the Biophysical Society, held Saturday, February 20 through Wednesday, February 24, 2027 at the Pennsylvania Convention Center in Philadelphia, PA, convening the international biophysics community.

2027 AAAS Annual Meeting

The multidisciplinary AAAS Annual Meeting convenes scientists, engineers, policymakers, educators, and journalists to examine how research, policy, media, and public trust shape scientific progress and evidence-informed action.

AAAI-27

The 41st Annual AAAI Conference on Artificial Intelligence at the Palais des Congres de Montreal, featuring technical papers, special tracks, invited speakers, workshops, tutorials, poster sessions, and competitions to promote AI research and scientific exchange.

Single Cell Biology: Expanding Potential Across Diseases

A Keystone Symposium bringing together single-cell genomics, spatial biology, perturbation technologies, computational methods, and clinical translation across high-burden diseases.

EMBO Postdoctoral Fellowships

Supports internationally mobile postdoctoral researchers in the life sciences for up to two years, including a salary or stipend, a relocation allowance and support for fellows with children. Applications accepted throughout the year; next hard cutoff 22 January 2027, 14:00 CET.

Neurodevelopmental Disorders: Mechanisms and Therapeutics

A Keystone Symposium connecting genetics, functional genomics, developmental neurobiology, and industry to identify convergent mechanisms and therapeutic opportunities in neurodevelopmental disorders.

SICB 2027

Annual meeting of the Society for Integrative and Comparative Biology at the David L. Lawrence Convention Center in Pittsburgh, PA, spanning research across integrative and comparative biology.

Cell Bio 2026 - An ASCB|EMBO Meeting

Joint ASCB|EMBO meeting at the San Diego Convention Center bringing together the cell biology community to share scientific discoveries, network with colleagues across career stages, and explore new research areas and methodologies.

NeurIPS 2026

The Fortieth Annual Conference on Neural Information Processing Systems brings together interdisciplinary machine-learning research through peer-reviewed sessions, invited talks, demonstrations, tutorials, workshops, and an exposition.

NeurIPS 2026

The Fortieth Annual Conference on Neural Information Processing Systems, organized by the Neural Information Processing Systems Foundation, with the main meeting in Sydney, Australia (Dec 6-12) and satellite venues in Atlanta, Georgia and Paris, France (Dec 9-13).

Neuromodulation of Circuit Plasticity: From Adaptive Behavior to Precision Therapeutics

Kuan Hong Wang examines how dopaminergic, cannabinoid, and neuroimmune signaling regulate circuit plasticity across development, experience, and disease, and how cross-species work may inform selective therapies.

RSNA 2026

RSNA 2026: At the Center of Care - the Radiological Society of North America's annual meeting at McCormick Place, Chicago, exploring the central role radiologists and imaging scientists play in ensuring better patient care, with technical exhibits Nov 29-Dec 2.

Wellcome Career Development Awards — November 2026 round

Funding for mid-career researchers from any discipline who have the potential to become international research leaders and whose work relates to human life, health and wellbeing.

National Science Foundation Translation to Practice (NSF TTP)

NSF support for translating research discoveries and innovations toward practical use through the TTP Translational and Partnership tracks.

Neuroscience 2026

The Society for Neuroscience annual meeting brings the neuroscience community together for a multi-day scientific program, professional development, networking, and presentation of research spanning the field. Registration and housing are open for the Washington, DC meeting.

EMBO Workshop: Proteostasis shaping health span: from protein folding to failure

This EMBO Workshop examines how protein synthesis, folding, trafficking, and degradation shape health across the lifespan, connecting fundamental proteostasis mechanisms with ageing and degenerative disease.

Knight Initiative - Rosenkranz Aging Symposium

An in-person Stanford symposium highlighting recent progress in brain resilience and aging research, followed by a neuroscience poster session featuring work from the Stanford community.

NSF SBIR/STTR Pilot Emphasis on Scientific Instrumentation

NSF funding for startups and small businesses developing next-generation scientific instruments, experimental platforms and enabling technologies for research.

McKnight Scholar Awards

Supports exceptional young neuroscientists in the early stages of establishing an independent laboratory and research career. Up to ten scholars receive a total award of $225,000 paid in equal installments of $75,000 in 2027, 2028, and 2029; applications open early August 2026.

The 2026 Picower Lecture with Richard L. Huganir

Richard L. Huganir discusses research on the molecular mechanisms that regulate glutamate receptors, the brain's major excitatory neurotransmitter receptors, and thereby modulate communication between neurons.

Towards Biologically Informed Subgroups Across Neurodevelopmental Disorders

Jason Lerch presents a translational neuroimaging analysis spanning mouse models and human MRI cohorts to identify biologically informed subgroups across autism and related neurodevelopmental conditions.

A Riemannian Geometry Perspective on Foundation Models

Oden Institute Seminar by Rex Ying (Yale University) on how non-Euclidean geometries, particularly hyperbolic geometry, can enhance foundation models by better capturing hierarchies and symmetries in real-world data, with applications across Transformers, language model training, multimodal systems, and recommender systems.

ASHG 2026 Annual Meeting

Annual meeting of the American Society of Human Genetics at the Palais des Congres de Montreal, gathering 7,500+ attendees from 75 countries for 100+ scientific sessions and 240 exhibitors and sponsors across human genetics and genomics research.

CBD 2026: The Narrating Brain: The Default Mode Network, the Self, and Consciousness in the Age of AI with Vinod Menon, PhD

Vinod Menon examines the brain's default mode network as a foundation for autobiographical memory, self-related processing, and consciousness, and considers how these functions compare with current artificial intelligence systems. The virtual session is part of Stanford's Contemplation by Design Summit.

Wu Tsai Neurosciences Institute Symposium 2026: Building the Brain

This Stanford symposium examines how molecular, cellular, and circuit-level advances in neurodevelopment shape understanding of behavior and health, with scientific talks, awards, and a poster session.

ERC Starting Grant

ERC-2027-STG call, opened 22 July 2026. Supports early-career researchers of any nationality to build their own teams and pursue frontier research in any field, with grants of up to EUR 1.5 million for 5 years (additional funding possible for relocation or major costs).

UKRI Translation: BBSRC Proof of Concept 2026

Funding to translate bioscience research into innovations such as products, services and solutions with real-world economic, societal and environmental impact. Opened 5 August 2026; £3,000,000 total, £100,000–£800,000 per project at 80% full economic cost.

EMBL Entrepreneurial Minds - Beyond the Structure: My Journey Through Science, Innovation and Life Choices

Ilaria Ferlenghi discusses a career spanning structural biology, cryo-electron microscopy, vaccine research and development, and the growing role of artificial intelligence and machine learning in scientific innovation and entrepreneurship.

EMBO Workshop: Organelle dynamics in health and disease: bridging molecules to organisms

This EMBO Workshop connects organelle contact sites and cytoskeletal interactions with metabolism, signalling, and trafficking, and examines their relevance to neurodegeneration, cancer, and other diseases.

ASM Bioinformatics, Genomics and Big Data Conference

The ASM Bioinformatics, Genomics and Big Data Conference brings the microbiology community together around bioinformatics, genomics, and large-scale data methods, with registration open for the 2026 meeting in Washington, DC.

Engineering Research Initiation (ERI)

NSF support for new engineering investigators at eligible non-R1 institutions to initiate research programs, build capacity and advance their careers.

Mathematical Foundations of Artificial Intelligence (MFAI)

NSF support for interdisciplinary collaborations developing mathematical and theoretical foundations for explainable, reliable, sustainable and trustworthy artificial intelligence.

Building a Brain, One Cell at a Time: Reading the Developmental Instructions Behind Human Neural Diversity

Tom Nowakowski explains lineage barcoding and single-cell sequencing approaches for reconstructing neural stem-cell family trees and early wiring programs in developing mouse and human brains.

Superconducting qubit control on millisecond timescales: from rapid feedback to new qubit dynamics

Seminar by Morten Kjaergaard (Niels Bohr Institute, University of Copenhagen) on rapid FPGA-based feedback for superconducting qubits, including sparse-sampling techniques and on-FPGA inference enabling millisecond-timescale T1 estimation, ~100 ms readout optimization, and over 74,000 consecutive recalibrations in closed-loop operation.

Molecular mechanisms in evolution and ecology

This EMBO workshop brings experimental and computational researchers together around molecular mechanisms of adaptation, evolutionary dynamics, microbial communities, symbiosis, biodiversity, and cell-environment interactions.

BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)

This NIH BRAIN Initiative opportunity supports the development of theories, computational models, and analytical methods for large-scale, complex brain data. Priority is given to novel capabilities for integrating and interpreting physiological, anatomical, connectivity, behavioral, and cell-type-specific data emerging from BRAIN Initiative research.

BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)

This NIH BRAIN Initiative opportunity supports dissemination of existing resources into neuroscience research practice. Activities may include distribution of tools and reagents, training in new technologies, access to technology platforms or specialized facilities, minor improvements to resource delivery, and adaptations for user communities.

Colloquium on the Brain and Cognition with Christopher Harvey, PhD, Harvard University

Picower Institute Colloquium on the Brain and Cognition featuring Christopher Harvey, PhD, of Harvard University, held in Singleton Auditorium (46-3002) at MIT Building 46, 43 Vassar Street.

Engineering human myelination in vitro: Mechanobiologically compatible platforms for CNS drug discovery

UCL Department of Neuroinflammation Seminar by Professor Emad Moeendarbary (Professor of Cell Mechanics and Mechanobiology, UCL Mechanical Engineering) on how biophysical factors such as substrate stiffness and axon geometry regulate oligodendrocyte behavior and myelin formation, presenting the AxoMetic in vitro myelination platform for discovery of remyelinating therapies.

Targeted Grants to Institutes

Supports established institutes and research centers in mathematics and the physical sciences to strengthen contacts within the international scientific community; up to $750,000 (inclusive of 20% indirect costs) over a three-year award period, with up to ten grants each year.

Learning the Regulatory Code with AI

MIT Biology Colloquium Series talk by Peter Koo (Cold Spring Harbor Laboratory), hosted by Yunha Hwang, on using AI to learn the gene regulatory code.

Postdoctoral Research Fellowships in Biology (PRFB)

NSF postdoctoral fellowships supporting early-career scientists who combine artificial intelligence with biological research and training to advance biotechnology innovation.

Bernstein Conference 2026

Annual conference of the Bernstein Network Computational Neuroscience, bringing together students, postdocs and PIs from around the world to meet and discuss new scientific discoveries in computational neuroscience. Satellite workshops Sep 28-29, main conference Sep 29-Oct 1 at Goethe University, Campus Westend, Frankfurt am Main.

6th Annual Precision Mental Health Symposium: From Circuits to Mindsets: Precision Mental Health in the Real World

Stanford's annual Precision Mental Health Symposium explores how neuroscience, psychiatry, data science, and artificial intelligence can translate brain research into real-world mental-health care. Themes include circuits and cognition, biomarkers and neuroimaging, rapid-acting interventions, neuromodulation, and precision therapeutics.

Innovation for the Aging Brain

The MIT Aging Brain Initiative brings together work in molecular imaging, cognition, chemistry, bioengineering, neurodegeneration, and artificial intelligence to address brain aging and Alzheimer's prevention.

Spin-directed Chiral Symmetry Breaking

Chemistry seminar by Prof. Yves Geerts (Université Libre de Bruxelles) on historical attempts by Pasteur and Curie to direct chiral symmetry breaking with external fields, why they failed, and how chirality-induced spin selectivity (CISS) under non-equilibrium conditions now enables enantiomer separation and control of molecular handedness.

Dark Causal Inference: Why Most Causal Inference in Epidemiology is Invisible

Harvard T.H. Chan School of Public Health Department of Epidemiology seminar by Jeremy Labrecque, PhD, MSc (Assistant Professor of Epidemiology and Causal Inference, Erasmus MC, Rotterdam) on 'dark causal inference' — implied but unstated causal reasoning that pervades epidemiology — the misuse of 'association' language, and gaps in teaching causal reasoning.

Stem Cell & Developmental Biology Early Career Symposium

A three-day scientific symposium led by early-career scientists, combining invited talks, selected short talks, poster sessions, workshops, networking, and cross-disciplinary exchange in stem cell and developmental biology.

Invertebrate oncology: ancient origins of tumor-host interactions

MIT Biology Colloquium Series talk by David Bilder (University of California, Berkeley), hosted by Yukiko Yamashita, on invertebrate oncology and the ancient evolutionary origins of tumor-host interactions.

HFSP Accelerator Grant 2027

The HFSP Accelerator Grant helps eligible HFSP Research Grant teams add an independent group leader from an underrepresented eligible country, bringing complementary expertise and strengthening international life-science collaboration.

The Pyrocene: Living in a New Age of Fire

Cary Institute lecture with environmental historian Stephen Pyne (professor emeritus, Arizona State University) in conversation with Cary forest ecologist Winslow Hansen, on humanity's evolving relationship with fire, why destructive megafires have increased, the role of climate and land-use decisions, and pathways toward restoring ecological fire balance.

Deciphering the Dynamics of the Unconscious Brain under General Anesthesia

Stanford Neurosciences Seminar Series talk by Emery Brown (Massachusetts Institute of Technology, Neuroscience Statistics Research Lab) on deciphering the dynamics of the unconscious brain under general anesthesia, hosted by the Wu Tsai Neurosciences Institute.

ERC Proof of Concept Grant

ERC-2026-PoC call funding ERC grantees to explore the innovation potential of their frontier research; a lump sum of EUR 150,000 for a period of 18 months, with one application per Principal Investigator per call.

Ahlfors Lectures: Mohammed Abouzaid

Two-lecture series by Mohammed Abouzaid (Stanford): 'Framed bordism and nearby Lagrangians' (September 16) and 'Complex bordism and Hamiltonian fibrations' (September 17), on bordism-theoretic approaches to Lagrangian embeddings in symplectic manifolds and Arnold's nearby Lagrangian conjecture.

Kirk Public Lecture | An operator-algebraic perspective on topological orders

Kirk Public Lecture at the Isaac Newton Institute by Yoshiko Ogata (Kyoto University) on how macroscopic properties of matter emerge from quantum particle interactions and the classification of topological order from an operator-algebraic perspective in mathematical physics.

CMSA/Tsinghua Math-Science Literature Lecture: Robert Gompf

Robert E. Gompf (University of Texas, Austin) lectures on 'On classifying smoothings of R^4 - from the beginning to the present', tracing how 4-manifold topology emerged from the breakthroughs of Freedman and Donaldson and how Euclidean 4-space admits exotic smoothings that resist classification by countable numerical invariants.

Reconstructing the human past: using ancient and modern genomics

This EMBO-EMBL symposium joins population genetics, bioinformatics, microbiology, anthropology, archaeology, and history to study human variation, ancient pathogens, domestication, analytical methods, and ethics in paleogenomics.

NIH Director’s Early Independence Award (DP5 Clinical Trial Optional)

The NIH Common Fund enables exceptional junior scientists to bypass a traditional postdoctoral period and launch an independent research career at a supportive institution.

Changing Perspectives on Self Control

Yuko Munakata presents evidence challenging capacity-only accounts of self-control and explains how experience, effort, and expected payoff shape executive-function engagement and later outcomes.

Mortality Displacement: Sixty Years of Debate and Consequences

Harvard T.H. Chan School of Public Health Department of Epidemiology seminar by David Jones, MD, PhD (Chair, Department of the History of Science, Harvard; Professor of Epidemiology) on the sixty-year history of 'mortality displacement' — the contested idea that pollution crises kill people already close to death — and its implications for policy.

MSCA Postdoctoral Fellowships 2026

HORIZON-MSCA-2026-PF-01 call, open since 9 April 2026 with a budget of EUR 399.05 million expected to fund nearly 1,600 projects. European and Global Postdoctoral Fellowships help researchers acquire new skills through international, interdisciplinary and inter-sectoral mobility.

NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

RFA-RM-27-001, posted June 29, 2026 and currently open. The Pioneer Award supports individual scientists proposing pioneering, high-impact approaches to major challenges in biomedical or behavioral research; 8 awards expected from $8,000,000 in program funding.

Preparing for non-academic interviews

Industry recruiters and hiring managers share practical advice on preparing for non-academic interviews, followed by a live question-and-answer session for researchers exploring careers beyond academia.

ECCV 2026

The 19th European Conference on Computer Vision, the biennial premier research conference in computer vision and machine learning managed by the European Computer Vision Association, held at Malmo Arena and Malmomassan in Malmo, Sweden.

Chemical biology 2026

This EMBO workshop covers emerging chemical-biology research spanning computational protein design, big data and AI, technologies for probing and manipulating biology, chemical synthetic biology, and RNA.

Preparation of Tensor Network States

Isaac Newton Institute seminar in the 'Mathematics of many-body entanglement' (MMB) programme: Ignacio Cirac of the Max-Planck-Institut für Quantenoptik speaks on the preparation of tensor network states.

NIH Director’s Transformative Research Award (R01 Clinical Trial Optional)

The NIH Common Fund supports individuals or teams pursuing exceptionally innovative, unconventional research with the potential to create or overturn major paradigms across biomedical and behavioral science.

Project Grants in the Natural and Technical Sciences 2026

Supports fundamental research within the natural and technical sciences with potential future applications in life science, health science or sustainability; up to DKK 4 million per project from a DKK 77 million grant capital in 2026. Call opened 19 June 2026.

ERC Plus Grant 2026

The ERC Plus Grant supports a single principal investigator pursuing an ambitious, transformative frontier-research project beyond the scope of existing ERC grants, with four to seven years of lump-sum funding.

A new view of plankton in the global ocean: celebrating 10 years of Tara Oceans

This EMBL conference connects oceanography, microbial ecology, evolution, genomics, imaging, remote sensing, modeling, and deep learning to examine a decade of Tara Oceans discoveries and open data.

Pathways to Enable Secure Open-Source Ecosystems (PESOSE)

NSF support for creating, strengthening and sustaining secure open-source ecosystems that advance scientific and technological innovation and broaden participation.

Project Grants in Bioscience and Basic Biomedicine

Novo Nordisk Foundation open-competition project grants of DKK 1–4.5 million over 1–3 years for fundamental research anchored at a Danish university, hospital or non-profit research institution; call opened 18 June 2026, with an additional DKK 12 million reserved for a strategic theme on microbiota-host interactions.

ERC Advanced Grant

ERC-2026-ADG call, opened 28 May 2026. For established researchers with a track-record of significant research achievements, in any scientific field, hosted in an EU Member State or associated country; up to EUR 2.5 million for 5 years, with additional funding possible.

Wu Tsai Human Performance Alliance Research Symposium

Stanford's summer research symposium features a keynote by Jamie Zeitzer, undergraduate lightning talks, and a poster and demonstration session on human performance research.

Repurposing CRISPR to turn genes on and off

UC Berkeley Molecular & Cell Biology seminar (Divisions of Biochemistry, Biophysics & Structural Biology; Cell Biology, Development & Physiology; and Genetics, Genomics, Evolution & Development) by Luke Gilbert of UCSF on repurposing CRISPR systems to activate and silence genes.

Advancing CAR T Cell Therapy for Brain Tumors: Overcoming Barriers to Efficacy

Gladstone-UCSF Institute of Genomic Immunology Seminar by Christine Brown, PhD (Deputy Director, T Cell Therapeutics Research Laboratories) on developing and refining redirected CAR T cells for malignant brain tumors, including glioblastoma, tumor heterogeneity, immunosuppressive microenvironments, delivery routes, and manufacturing.

The exoplanet revolution and life in the Universe - Public Lecture & Panel Discussion

Public lecture by Prof. Didier Queloz, FRS (Jacksonian Professor of Natural Philosophy, Cambridge; Professor of Physics, ETH Zurich), organized by the Swiss Physical Society at EPFL, on how exoplanet discoveries transformed understanding of planet formation and the search for life signatures in planetary atmospheres. Free admission for the general public.

Transcription and chromatin

The seventeenth EMBL conference on transcriptional regulation covers polymerase function, chromatin modification and remodeling, epigenetic inheritance, genome topology, condensates, development, disease, and quantitative methods.

Massively Parallel Studies of Enhancer Function

UC Berkeley Molecular & Cell Biology seminar (Division of Genetics, Genomics & Development) by Barak Cohen of Washington University in Saint Louis on massively parallel experimental studies of enhancer function.

Chemical proteomics reveals post-translational remodeling of endosomal pathways during macrophage activation

Thesis presentation by Tiffany Zhang, graduate fellow in the Vinogradova Lab at The Rockefeller University, on chemical proteomics approaches revealing post-translational remodeling of endosomal pathways during macrophage activation. Open to the tri-institutional community.

NIH Director’s New Innovator Award Program (DP2 Clinical Trial Optional)

The NIH Common Fund supports exceptionally creative early-stage investigators pursuing bold, high-impact biomedical or behavioral research without requiring preliminary data.

Modeling Genetic Effects Across Contexts and Phenotypes

Convergence Seminar by Alexis Battle, PhD (Wu and Zhang Professor of Biomedical Engineering and Computer Science, Johns Hopkins University), on computational and machine-learning approaches for analyzing how genetic variation impacts gene regulation and disease, including noncoding sequences and rare variants.

Emerging NeuroTech: Ultrasound in Neuroscience

Two talks present emerging applications of ultrasound technology in neuroscience, spanning brain imaging and human-machine interaction. The in-person seminar is open to MIT researchers, students, and staff and is supported by the MIT School of Science and the Feng Lab at the McGovern Institute.

Emerging NeuroTech: Ultrasound in Neuroscience

MIT researchers and students are invited to two talks on emerging applications of ultrasound for non-invasive brain imaging, neural modulation and wearable human-machine interaction.

Career Awards at the Scientific Interface

CASI provides $560,000 over five years to bridge advanced postdoctoral training and the first years of faculty service for researchers from mathematics, physics, chemistry, computer science, statistics or engineering applying their expertise to biological questions. Pre-proposals due August 14, 2026, 3 pm EDT.

Defining profilin function in mammalian actin dynamics and cell behaviour

Klemens Rottner (Helmholtz Centre for Infection Research, Braunschweig) presents evidence that profilin acts as a master regulator of actin filament dynamics essential for cell migration and growth, controlling both formin- and Arp2/3 complex-dependent actin assembly pathways.

Using AI to Increase Your Intelligence & Enrich Humanity | Dr. Fei-Fei Li

Andrew Huberman and Fei-Fei Li discuss how artificial intelligence works, spatial intelligence, human cognition, creativity, learning, health and human agency.

Essentials: Control Your Brain Chemistry for Focus, Motivation & Well-Being

Andrew Huberman explains how key neuromodulators shape motivation, energy, focus and mood, with science-supported behavioral, nutritional and supplement strategies.

BI 243 Alison Barth: Learning as a Window to Cortex

Alison Barth explains how distinct neuron types contribute to cortical function and how learning can be used as an experimental window into the organization and plasticity of cortical circuits.

How Your Immune System Works & How to Improve It | Dr. Max Krummel

Andrew Huberman and immunologist Max Krummel discuss immune function, sleep, emotions, memory, the thymus, autoimmunity, cancer and immunization.

Briefing Chat: Orcas smashed a sunfish to bits — researchers aren’t sure why

Nature staff discuss a large survey of insect diversity in the Amazon and unusual orca behavior captured on video involving a sunfish.

Earthworks spotted in the Amazon hint at huge ancient civilization

Nature editors discuss nearly 400 structures that reveal the scale of the Aquiry civilization and tiny fossils of an early squid ancestor.

BI 242 Kathryn Nave: How Life Gets its Meaning and Intelligence

Kathryn Nave discusses how living systems acquire meaning and intelligence through organization, constraints, and active inference. The conversation connects the free-energy principle and organizational closure to questions about brains, cognition, agency, and the boundaries of intelligent life.

Briefing Chat: The 30 year-legacy of a science icon — Dolly the sheep

Nature staff revisit the landmark cloning of Dolly the sheep from an adult cell and discuss the first direct observation of ocean-floor crust being created.

Togetherness: How cooperation built the world

Science journalist Rowan Hooper joins the Nature Podcast to explore symbiosis, cooperation, and the importance of organisms working together across the living world.

BI 241 Johannes Jaeger: Agency and the Cyborg Myth

Paul Middlebrooks and Johannes Jaeger discuss agency in living systems, relevance realization, consciousness, energy efficiency and why biological organisms differ from artificial agents.

Audio long read: Is the peptide craze backed by science? The promise behind the hype

Nature examines the booming market for unregulated peptides and asks whether scientific evidence supports the health and wellness claims driving their popularity.

Briefing Chat: What tickling a chimpanzee can tell us about the evolution of speech

Nature staff discuss rhythmic laughter in apes, what it may reveal about the evolution of speech, and evidence that AI use can erode skills in medicine and computing.

When autistic kids grow up, Chapter 2: “You need to go to college”

Chapter 2 follows Tempest McDonald's journey through higher education after earning a high-school equivalency degree and becoming a single mother.

Adventures in Spin Labeling: Clinical Perfusion Imaging and the Path to Technical Innovation

Arterial spin labeling (ASL) MRI has become a vital tool in clinical neuroimaging, enabling noninvasive assessment of cerebral perfusion across a range of conditions including stroke, vascular malformations, and brain tumors. With broader clinical adoption, its practical strengths — as well as important limitations — have become increasingly clear.

Striatal activity in natural behavior

Decoding stress vulnerability

Although stress can be considered as an ongoing process that helps an organism to cope with present and future challenges, when it is too intense or uncontrollable, it can lead to adverse consequences for physical and mental health. Social stress specifically, is a highly prevalent traumatic experience, present in multiple contexts, such as war, bullying and interpersonal violence, and it has been linked with increased risk for major depression and anxiety disorders. Nevertheless, not all individuals exposed to strong stressful events develop psychopathology, with the mechanisms of resilience and vulnerability being still under investigation. During this talk, I will identify key gaps in our knowledge about stress vulnerability and I will present our recent data from our contextual fear learning protocol based on social defeat stress in mice.

Predictive Coding Light

Current machine learning systems consume vastly more energy than biological brains. Neuromorphic systems aim to overcome this difference by mimicking the brain’s information coding via discrete voltage spikes. However, it remains unclear how both artificial and natural networks of spiking neurons can learn energy-efficient information processing strategies. Here we propose Predictive Coding Light (PCL), a recurrent hierarchical spiking neural network for unsupervised representation learning. In contrast to previous predictive coding approaches, PCL does not transmit prediction errors to higher processing stages. Instead, it suppresses the most predictable spikes and transmits a compressed representation of the input. Using only biologically plausible spike-timing based learning rules, PCL reproduces a wealth of findings on information processing in visual cortex and permits strong performance in downstream classification tasks. Overall, PCL offers a new approach to predictive coding and its implementation in natural and artificial spiking neural networks

sensorimotor control, mouvement, touch, EEG

Traditionally, touch is associated with exteroception and is rarely considered a relevant sensory cue for controlling movements in space, unlike vision. We developed a technique to isolate and measure tactile involvement in controlling sliding finger movements over a surface. Young adults traced a 2D shape with their index finger under direct or mirror-reversed visual feedback to create a conflict between visual and somatosensory inputs. In this context, increased reliance on somatosensory input compromises movement accuracy. Based on the hypothesis that tactile cues contribute to guiding hand movements when in contact with a surface, we predicted poorer performance when the participants traced with their bare finger compared to when their tactile sensation was dampened by a smooth, rigid finger splint. The results supported this prediction. EEG source analyses revealed smaller current in the source-localized somatosensory cortex during sensory conflict when the finger directly touched the surface. This finding supports the hypothesis that, in response to mirror-reversed visual feedback, the central nervous system selectively gated task-irrelevant somatosensory inputs, thereby mitigating, though not entirely resolving, the visuo-somatosensory conflict. Together, our results emphasize touch’s involvement in movement control over a surface, challenging the notion that vision predominantly governs goal-directed hand or finger movements.

Consciousness at the edge of chaos

Over the last 20 years, neuroimaging and electrophysiology techniques have become central to understanding the mechanisms that accompany loss and recovery of consciousness. Much of this research is performed in the context of healthy individuals with neurotypical brain dynamics. Yet, a true understanding of how consciousness emerges from the joint action of neurons has to account for how severely pathological brains, often showing phenotypes typical of unconsciousness, can nonetheless generate a subjective viewpoint. In this presentation, I will start from the context of Disorders of Consciousness and will discuss recent work aimed at finding generalizable signatures of consciousness that are reliable across a spectrum of brain electrophysiological phenotypes focusing in particular on the notion of edge-of-chaos criticality.

Computational Mechanisms of Predictive Processing in Brains and Machines

Predictive processing offers a unifying view of neural computation, proposing that brains continuously anticipate sensory input and update internal models based on prediction errors. In this talk, I will present converging evidence for the computational mechanisms underlying this framework across human neuroscience and deep neural networks. I will begin with recent work showing that large-scale distributed prediction-error encoding in the human brain directly predicts how sensory representations reorganize through predictive learning. I will then turn to PredNet, a popular predictive coding inspired deep network that has been widely used to model real-world biological vision systems. Using dynamic stimuli generated with our Spatiotemporal Style Transfer algorithm, we demonstrate that PredNet relies primarily on low-level spatiotemporal structure and remains insensitive to high-level content, revealing limits in its generalization capacity. Finally, I will discuss new recurrent vision models that integrate top-down feedback connections with intrinsic neural variability, uncovering a dual mechanism for robust sensory coding in which neural variability decorrelates unit responses, while top-down feedback stabilizes network dynamics. Together, these results outline how prediction error signaling and top-down feedback pathways shape adaptive sensory processing in biological and artificial systems.

Developmental emergence of personality

The Nature versus Nurture debate has generally been considered from the lens of genome versus experience dichotomy and has dominated our thinking about behavioral individuality and personality traits. In contrast, the role of nonheritable noise during brain development in behavioral variation is understudied. Using the Drosophila melanogaster visual system, I will discuss our efforts to dissect how individuality in circuit wiring emerges during development, and how that helps generate individual behavioral variation.

A human stem cell-derived organoid model of the trigeminal ganglion

Choice between methamphetamine and food is modulated by reinforcement interval and central drug metabolism

High Stakes in the Adolescent Brain: Glia Ignite Under THC’s Influence

Prefrontal-thalamic goal-state coding segregates navigation episodes into spatially consistent parallel hippocampal maps

Computational bio-imaging via inverse scattering

Optical imaging is a major research tool in the basic sciences, and is the only imaging modality that routinely enables non-ionized imaging with subcellular spatial resolutions and high imaging speeds. In biological imaging applications, however, optical imaging is limited by tissue scattering to short imaging depths. This prevents large-scale bio-imaging by allowing visualization of only the outer superficial layers of an organism, or specific components isolated from within the organism and prepared in-vitro.

Harnessing Artificial Intelligence to Fight Infectious Diseases

Charlene Lancaster speaks with Cesar de la Fuente about using artificial intelligence to discover novel antibiotics from organisms and genetic sources spanning spiders, archaea, woolly mammoths, and humans.

Introduction to protocols.io: Scientific collaboration through open protocols

Research articles and laboratory protocol organization often lack detailed instructions for replicating experiments. protocols.io is an open-access platform where researchers collaboratively create dynamic, interactive, step-by-step protocols that can be executed on mobile devices or the web. Researchers can easily and efficiently share protocols with colleagues, collaborators, the scientific community, or make them public. Real-time communication and interaction keep protocols up to date. Public protocols receive a DOI and enable open communication with authors and researchers to foster efficient experimentation and reproducibility.

Microglia regulate remyelination via inflammatory phenotypic polarization in CNS demyelinating disorders

Top-down control of neocortical threat memory

Accurate perception of the environment is a constructive process that requires integration of external bottom-up sensory signals with internally-generated top-down information reflecting past experiences and current aims. Decades of work have elucidated how sensory neocortex processes physical stimulus features. In contrast, examining how memory-related-top-down information is encoded and integrated with bottom-up signals has long been challenging. Here, I will discuss our recent work pinpointing the outermost layer 1 of neocortex as a central hotspot for processing of experience-dependent top-down information threat during perception, one of the most fundamentally important forms of sensation.

MRI investigation of orientation-dependent changes in microstructure and function in a mouse model of mild traumatic brain injury

Convergent large-scale network and local vulnerabilities underlie brain atrophy across Parkinson’s disease stages

Biomolecular condensates as drivers of neuroinflammation

Organization of thalamic networks and mechanisms of dysfunction in schizophrenia and autism

Thalamic networks, at the core of thalamocortical and thalamosubcortical communications, underlie processes of perception, attention, memory, emotions, and the sleep-wake cycle, and are disrupted in mental disorders, including schizophrenia and autism. However, the underlying mechanisms of pathology are unknown. I will present novel evidence on key organizational principles, structural, and molecular features of thalamocortical networks, as well as critical thalamic pathway interactions that are likely affected in disorders. This data can facilitate modeling typical and abnormal brain function and can provide the foundation to understand heterogeneous disruption of these networks in sleep disorders, attention deficits, and cognitive and affective impairments in schizophrenia and autism, with important implications for the design of targeted therapeutic interventions

Temporal Hierarchies in Reward and Behavioral Control

Spike train structure of cortical transcriptomic populations in vivo

The cortex comprises many neuronal types, which can be distinguished by their transcriptomes: the sets of genes they express. Little is known about the in vivo activity of these cell types, particularly as regards the structure of their spike trains, which might provide clues to cortical circuit function. To address this question, we used Neuropixels electrodes to record layer 5 excitatory populations in mouse V1, then transcriptomically identified the recorded cell types. To do so, we performed a subsequent recording of the same cells using 2-photon (2p) calcium imaging, identifying neurons between the two recording modalities by fingerprinting their responses to a “zebra noise” stimulus and estimating the path of the electrode through the 2p stack with a probabilistic method. We then cut brain slices and performed in situ transcriptomics to localize ~300 genes using coppaFISH3d, a new open source method, and aligned the transcriptomic data to the 2p stack. Analysis of the data is ongoing, and suggests substantial differences in spike time coordination between ET and IT neurons, as well as between transcriptomic subtypes of both these excitatory types.

Generation and use of internal models of the world to guide flexible behavior

NF1 exon 51 alternative splicing: functional implications in Central Nervous System (CNS) Cells

Memory Decoding Journal Club: Functional connectomics reveals general wiring rule in mouse visual cortex

Functional connectomics reveals general wiring rule in mouse visual cortex

The tubulin code in neuron health and disease : focus on detyrosination

Astrocytes: From Metabolism to Cognition

Different brain cell types exhibit distinct metabolic signatures that link energy economy to cellular function. Astrocytes and neurons, for instance, diverge dramatically in their reliance on glycolysis versus oxidative phosphorylation, underscoring that metabolic fuel efficiency is not uniform across cell types. A key factor shaping this divergence is the structural organization of the mitochondrial respiratory chain into supercomplexes. Specifically, complexes I (CI) and III (CIII) form a CI–CIII supercomplex, but the degree of this assembly varies by cell type. In neurons, CI is predominantly integrated into supercomplexes, resulting in highly efficient mitochondrial respiration and minimal reactive oxygen species (ROS) generation. Conversely, in astrocytes, a larger fraction of CI remains unassembled, freely existing apart from CIII, leading to reduced respiratory efficiency and elevated mitochondrial ROS production. Despite this apparent inefficiency, astrocytes boast a highly adaptable metabolism capable of responding to diverse stressors. Their looser CI–CIII organization allows for flexible ROS signaling, which activates antioxidant programs via transcription factors like Nrf2. This modular architecture enables astrocytes not only to balance energy production but also to support neuronal health and influence complex organismal behaviors.

Targeted Grants in MPS

Supports high-risk projects of exceptional promise and scientific importance in mathematics and the physical sciences, with funding for up to five years; letters of intent are accepted on a rolling basis and there is no recommended or assumed funding level.

Computer and Information Science and Engineering: Future Computing Research (Future CoRe)

Active NSF solicitation (NSF 25-543) funding core computer and information science and engineering research. Proposals are accepted anytime, with target dates (second Thursday in September and first Thursday in February annually) for panel review cycles; projects up to $1,000,000 and 4 years.

EPSRC standard research grant, Nov 2023: responsive mode

EPSRC's responsive-mode standard research grant, 'Open - no closing date': applications are accepted continuously and batched internally for assessment. No specified upper limit on grant value or project length; EPSRC funds 80% of the full economic cost.

MRC: research grant: applicant-led

MRC's applicant-led responsive research grant, explicitly 'Open - no closing date': submit when the application is ready. No upper funding limit — the amount should be appropriate to the project — for up to five years, with MRC funding 80% of full economic cost.

Individual Research Grants

DFG's central individual funding programme for research projects in all disciplines: 'The first proposal may be submitted at any time.' Duration is based on individual project needs, as a rule several years, with modules for staff, instrumentation and other project costs.

Division of Integrative Organismal Systems Core Programs (IOS)

NSF core-programs solicitation (NSF 24-546) supporting research on integrative organismal biology, including behavioral, developmental, neural and physiological systems. Proposals are accepted anytime, with an estimated $70,000,000 available per fiscal year across ~150 standard or continuing grants.