Towards understanding the microcircuit in monkey primary visual cortex in-vivo
Nicole Carr, Shude Zhu, Kenji Lee, Xiaomo Chen, Ruobing Xia, Alec Perliss, Tirin Moore, Chandramouli Chandrasekaran · COSYNE 2023
Sat, Mar 11, 2023
The primary visual cortex (V1) is fundamental for visual processing. Transcriptomics suggests that the microcircuit in V1 consists of many inhibitory and excitatory cell types1. However, exactly how those diverse cell populations participate in visual cognition in vivo is unknown. To address this question, we recorded from V1 of two anesthetized monkeys using high-density Neuropixel probes across all layers of cortex2. We identified single neuron waveforms using Kilosort2, followed by rigorous manual curation. Our final dataset was composed of 801 negative spiking neurons (from 2529 units, 5 s