Topic: landmark cells

Recent theoretical work has proposed that hippocampus acts as a binding site for sensory stimuli and a task coordinate system, each represented in the entorhinal cortex. Since this coordinate system path-integrates, incoming sensory observations can be inferred rather than learned. Here, we show that (1) a similar mechanism can learn representations that predict actions rather than stimuli. This mechanism supports zero-shot action prediction – a significant departure from current theoretical frameworks for action-learning. (2) The learned representations resemble object-vector and landmark cel

Successful navigation requires the integration of egocentric (body-centered) and allocentric (world-centered) strategies. Previous studies have shown how these two systems could be integrated by coordinating different functional cell types in the medial entorhinal cortex (MEC): grid cells, which are thought to serve as path integrators encoding egocentric information, and landmark cells, which encode allocentric information [1]. Theoretical work has shown how landmark cells could learn to serve as an error correction mechanism to grid cells via Hebbian plasticity, and experiments have found th