Topic: large-scale electrophysiology

Understanding brain activity requires large-scale electrophysiology recording with a single-cell resolution. Over the past decades, the number of electrodes allowed for simultaneous recording doubled approximately every 7 years. Large data from high-density electrodes stress every part of the recording system, including data transmission, storage, and processing, and demands high power. Developing an energy-efficient method to compress the data with minimal distortion is necessary.Spikes are the sparse information carrier in the neural network. The proposed method, focused on spikes, consists

Understanding the dynamic interplay between neuromodulatory systems and neuronal circuit dynamics is crucial for deciphering the underpinnings of complex behaviors. Noradrenergic signaling is widespread throughout the body and the brain and plays a pivotal role in the implementation of physiological processes and brain network configuration across arousal states. Yet, unraveling the causal relationship between norepinephrine release and concomitant neuronal dynamics poses a formidable challenge due to the intrinsic coupling of noradrenergic activity with behavioral changes.To resolve this conu