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Topic: low-rank perturbation

Seminar
1 seminar
ePoster
1 ePoster

In Computational Neuroscience and Dynamical Systems

ePoster · Computational Neuroscience

Neural-astrocyte interaction enables contextually guided circuit dynamics

Giacomo Vedovati, Thomas J. Papouin, ShiNung Ching · COSYNE 2023

Fri, Mar 10, 2023

Recurrent neural networks, a ubiquitous construct in machine intelligence, have become a powerful hypothesis-generating tool in theoretical neuroscience. Such networks can be used to examine potential circuit mechanisms associated with a variety of cognitive functions. Here, we use recurrent networks to engage a new theoretical question: the potential role of astrocytes in neural computation. Astrocytes are highly abundant cells in the cortex that are capable of modulating many facets of neural dynamics, including excitability, synaptic efficacy and plasticity. However, despite this modulatory

Seminar · Computational Neuroscience

Flexible motor sequence generation by thalamic control of cortical dynamics through low-rank connectivity perturbations

Laureline Logiaco · Center for Theoretical Neuroscience, Columbia University

Wed, Mar 9, 2022 · 17:35 UTC

One of the fundamental functions of the brain is to flexibly plan and control movement production at different timescales to efficiently shape structured behaviors. I will present a model that clarifies how these complex computations could be performed in the mammalian brain, with an emphasis on the learning of an extendable library of autonomous motor motifs and the flexible stringing of these motifs in motor sequences. To build this model, we took advantage of the fact that the anatomy of the circuits involved is well known. Our results show how these architectural constraints lead to a prin