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Lymnaea stagnalis

6 ePosters

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Cellular and molecular footprint of aging in a defined neuronal network encoding associative memory

István Fodor, Bence Gálik, Péter Urbán et al. · FENS Forum 2024

…such model is the great pond snail (Lymnaea stagnalis), which has been used extensively to study cognitive aging.We made the neuronal transcriptome assembly of Lymnaea and identified several evolutionarily conserved homolog sequences to genes involved in aging, age-related memory impairment, and neurodegenerative diseases of vertebrates including humans. Using young (3-4

Neuroscience

Effects of alprazolam on anxiety-related behavior in an invertebrate model: Advancing translational neuroscience

Veronica Rivi, Johanna Maria Catharina Blom, Luca Pani et al. · FENS Forum 2024

…Among them, the pond snail Lymnaea stagnalis serves as an effective model organism for Translational Neuroscience due to its relatively simple CNS and open circulatory system, simplifying the exploration of the complexity of conserved molecular pathways and allowing to investigate how drugs can modulate neuronal functions and behaviors. In this study, we discovered that, despite never encountering natural predator

Neuroscience

…In the pond snail Lymnaea stagnalis, epicatechin facilitates memory formation through conditioned taste aversion (CTA) training. These snails were categorized into two groups: "good learner" and "poor learner", based on their feeding behaviour 24hours after CTA training. The "good learner" snails showed at least a 40% reduction in feeding behaviour compared to the pre-test levels, while the others were categorized as "poor learner". This study first investigated the effe

Neuroscience