Topic: macaque brain

Cortical functions result from the conjoint activity of different, reciprocally connected areas working together as large-scale functionally specialized networks. In the macaque brain, neural tracers and functional data have provided evidence for functionally specialized large-scale cortical networks involving temporal, parietal, and frontal areas. One of these networks, the lateral grasping network, appears to play a primary role in controlling hand action organization and recognition. Available functional and tractograpy data suggest the existence of a human counterpart of this network.

Recent advances in neuronal recording technology have facilitated the development of large-scale, high-density microelectrode arrays resulting in a substantial increase (>10x) in the number of neurons that can be studied simultaneously within a localized area of neural tissue. A prime example is the recent development of the Neuropixels probe, which consists of a high-channel count Si shank with continuous, dense, programmable recording sites (~1000/cm). Neuropixels probes have transformed neurophysiological studies in rodent models by enabling recording from large populations of neurons anywh