Topic: mammalian cell culture

A January–June 2027 placement with the Biotherapeutics Discovery team in Cambridge, Massachusetts. Work focuses on evaluating and improving therapeutic antibodies and VHH candidates through binding, biophysical and cell-based assays. Activities include protein production and purification, mammalian cell culture, ELISA, Octet measurements, size-exclusion chromatography and assessment of thermal stability. Results support the progression of discovery programmes toward clinical development.

Join the mRNA Science team for a January–June 2027 placement in Cambridge, Massachusetts. Experiments compare mRNA sequences and chemical modifications using mammalian cell culture, transfection, protein-expression measurements and biochemical assays. The student generates and interprets experimental data and may also contribute to cloning, plasmid preparation and in vitro transcription. Work supports the evaluation of mRNA reagents for gene editing research.