Mammalian cortex

…are compared with changes in the mammalian cortex.

…might help explain diversity in the mammalian cortex and retina.

…of information representation in the mammalian cortex. However, the mechanisms underlying the modulation of neuronal ensembles yet remain to be fully understood. Here, we investigated external input-dependent modulation of neuronal ensembles in cultured neuronal networks with modular connectivity mimicking the mammalian cortex. The modular neuronal networks were fabricated by growing cultured rat cortical neurons in microfluidic devices. A fraction of the neurons was stimulated using optogeneti

The mammalian cortex is complex, consisting of many functionally distinct areas. Understanding how this diversification occurs remains a major goal. Interneurons in the adult mouse cortex are diverse, they can be defined based on developmental origin, distinct morphology, physiological and molecular properties (e.g. parvalbumin-expressing basket cells). Despite making up approximately 1/6 of the total neuronal population we do not currently have a cortex-wide map of interneurons.Using transgenic mice to label cells we have mapped the distribution of all interneurons, of 2 broad populations (MG