ePoster · Neuropharmacology
Promnesic, anxiolytic, and antioxidant effects of mansorin A and mansonone G in the okadaic acid-induced zebrafish model of Alzheimer’s disease
Iasmina Honceriu, Lucian Hritcu · FENS Forum 2024
Dementia, a complex, incurable clinical syndrome marked by progressive cognitive decline, encompasses various types, with Alzheimer's disease (AD) being the most prevalent. The annual increase in AD cases underscores the urgency for innovative antidementia treatments. Mansorin A (MA) and mansonone G (MG) exhibit antioxidant effects on the central nervous system. Given the close association between oxidative stress and AD pathology, MA and MG might alleviate AD-like symptoms. To investigate the anti-dementia potential of MA and MG, the promnesic, anxiolytic, and antioxidant potential of MA and