Topic: manual curation

Build a small-RNA analysis workflow from raw reads to curated microRNA annotations. Participants assess sequencing quality with miRTrace, retrieve public datasets and reproduce analyses and figures from published studies. Practical work combines MirMachine, miRTrace and MirMiner with genomic context and annotation standards, then examines false positives and missing genes through manual curation. The emphasis is on defensible identification of regulatory microRNAs and critical assessment of published predictions. Sessions: 23–26 November, 12:00–17:00 daily, Europe/Berlin (CET, UTC+01:00). Li

Much development has been directed toward improving the performance and automation of spike sorting. This continuous development, while essential, has contributed to an over-saturation of new, incompatible tools that hinders rigorous benchmarking and complicates reproducible analysis. To address these limitations, we developed SpikeInterface, a Python framework designed to unify preexisting spike sorting technologies into a single codebase and to facilitate straightforward comparison and adoption of different approaches. With a few lines of code, researchers can reproducibly run, compare, and