Topic: memory circuits

We learn different rules that can switch depending on context. When the rule depends on context, the context is important to learn to differentiate the rewarded choice in different contexts. While it has previously been shown that the reinstatement of context guides decisions for reward, it is less clear how or whether context-based reactivation guides the efficient learning of reward and context associations. We hypothesize that representations of the context are used to guide learning of associations between context and reward. We test whether this context is retrieved from memory circuits p

We use the olfactory system and forebrain of (adult) zebrafish as a model to analyze how relevant information is extracted from sensory inputs, how information is stored in memory circuits, and how sensory inputs inform behavior. A series of recent findings provides evidence that inhibition has not only homeostatic functions in neuronal circuits but makes highly specific, instructive contributions to behaviorally relevant computations in different brain regions. These observations imply that the connectivity among excitatory and inhibitory neurons exhibits essential higher-order structure that