Memory performance

…affecting both anxiety levels and memory performance, with inconsistent results.

…which correlates to decreased memory performance and disease severity. Two neurological cell populations, the noradrenergic (NA) neurons in the locus coeruleus (LC) and the parvalbumin (PV)-positive cortical interneurons are involved in the regulation of sleep spindles. However, the interplay o

…or postpone these changes, improving memory, learning, and cognitive abilities, but may not always yield positive results. In this study, we examined the impact of 30% DR (70% of ad libitum daily intake) during adolescence on the short-term (STM) and long-term (LTM) memory performance in 6- and 18-month-old female Wistar rats. The effects of DR were examined in three onsets and durations: DR1 (28th to 35th day of life), DR2 (35th to 42nd day

Memory impairment is a common cognitive deficit in temporal lobe epilepsy (TLE). The hippocampus is severely altered in TLE exhibiting multiple anatomical changes that lead to a hyperexcitable network capable of generating frequent epileptic discharges and seizures. In this study we investigated whether hippocampal involvement in epileptic activity drives working memory deficits using bilateral LFP recordings from CA1 during task performance. We discovered that epileptic mice experienced focal rhythmic discharges (FRDs) while they performed the spatial working memory task. Spatial correlation

The role of attention in working memory remains controversial, but there is some agreement on the notion that the focus of attention holds mnemonic representations in a privileged state of heightened accessibility in working memory, resulting in better memory performance for items that receive focused attention during retention. Closely related, representations held in the focus of attention are often observed to be robust and protected from degradation caused by either perceptual interference (e.g., Makovski & Jiang, 2007; van Moorselaar et al., 2015) or decay (e.g., Barrouillet et al., 2007)

Episodic memory performance decreases with advancing age. According to theoretical models, such memory decline might be a consequence of age-related reductions in the ability to form distinct neural representations of our past. In this talk, I want to present our new age-comparative fMRI study investigating age-related neural dedifferentiation across different representational levels. By combining univariate analyses and searchlight pattern similarity analyses, we found that older adults show reduced category selective processing in higher visual areas, less specific item representations in oc