Memory trace

…for example, as a signature of the memory trace in the network. I will first discuss the inference of the timescales from the neuroscience data comprised of the short trials and introduce a new unbiased method. Then, I will apply the method to the data recorded from a local population of cortical neurons from the visual area V4. I will demonstrate that the ongoing spiking activity unfolds across at least two distinct timescales - fast and slow - an

…are decreased when disrupting the memory trace in a premotor region in a simple visuomotor task. In additi

…behavioral drive, forming a memory trace. But if the predictor is presented as one of two options, the optimal response is uncertain and depends on the alternative. Can a single memory trace evoke different behaviors, depending on stimulus context? We used optogenetics in Drosophila to form an odor-punishment association restricted to a single set of synapses, ie. a single memory trace. These flies showed flexible behavioral responses to a given

The head direction (HD) system is classically modeled as a ring attractor network which ensures a stable representation of the animal’s head direction. This unidimensional description popularized the view of the HD system as the brain’s internal compass. However, unlike a globally consistent magnetic compass, the orientation of the HD system is dynamic, depends on local cues and exhibits remapping across familiar environments5. Such a system requires mechanisms to remember and align to familiar landmarks, which may not be well described within the classic 1-dimensional framework. To search for