Develop theory for neuronal and metabolic activity in brain organoids, including sleep–wake behaviour, in the J. M. Schwarz Theory Group. Research connects physical learning and multiscale mechanics with experimental observations, collaborating with Orly Reiner and Yaakov Nahmias. The role includes student mentoring and an on-campus research presence. The initial appointment is one year with a possible second year. The employer lists the position as open until filled; the earlier priority-review date has passed.
Metabolic activity
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Effect of nutrient sensing by microglia on mouse behavior
Microglia are the brain macrophages, eliciting multifaceted functions to maintain brain homeostasis across lifetime. To achieve this, microglia are able to sense a plethora of signals in their close environment. In the lab, we investigate the effect of nutrients on microglia function for several reasons: 1) Microglia express all the cellular machinery required to sense nutrients; 2) Eating habits have changed considerably over the last century, towards diets rich in fats and sugars; 3) This so-called "Western diet" is accompanied by an increase in the occurrence of neuropathologies, in which m
Tue, Nov 7, 2023 · 12:15 UTC
Myelination: another form of brain plasticity
…in relation to its functional and metabolic activity. Myelin modifications are increasingly being implicated as a mechanism for sensory-motor learning and unpublished data f
Wed, Mar 10, 2021 · 15:00 UTC