Topic: metabolic diseases

Obesity and metabolic diseases are a top priority challenge for health systems. Monitoring changes in the body’s energy levels is a task of the hypothalamus which integrates the actions of peripheral hormones and nutrients with neural information. Among the cells involved, tanycytes play a key role. They are glial cells that line the third ventricle and mediate information about changes in the circulation to various hypothalamic nuclei. They regulate important neuroendocrine functions such as food intake and energy balance. Although tanycytes are known to integrate external and internal signal