Miniature microscopes

…brain Ca2+ imaging in the IPACL with miniature microscopes

Animals often seek knowledge of no apparent extrinsic value, suggesting that knowledge is a source of intrinsic value. Therefore, the desire to acquire information may be an innate motivational drive. We have developed a task in mice to study the neural mechanisms that compute the value of informative stimuli that drive information seeking. Mice are provided with odor cues in a center port that dictate entry into one of two side ports. The side ports offer water reward with identical probability and differ only in whether they provide an information odor cue that reveals the reward outcome. We