Topic: mitral and tufted cells

Animals depend on their senses for survival. Mice, who rely on olfaction to navigate the world, can rapidly identify odors within a single sniff across a wide range of concentrations. In the mouse olfactory bulb (OB), mitral and tufted cells (MTCs) respond to odors by changing both the rate and timing of spikes relative to inhalation, resulting in reliable, odor specific sequences that evolve over a single sniff. However, it remains unknown how sequential MTC activity is organized. Specifically, what defines the order in which MTCs fire, and what information is encoded in these sequences? To a

The sensory world is highly dynamic, and the temporal structure of stimuli contains rich information about the environment. Odour plumes are shaped by complex airflow that imprint information about the nature and spatial organisation of the olfactory environment onto their temporal dynamics. Whilst insects and mammals alike can discern high-frequency information, how temporal properties of the olfactory environment are represented in the brain remains largely unknown. Here, we presented temporally rich and systematically varying odour stimuli whilst electrically recording from the output neuro