Molecular glues

…inhibitors, PROTACs, molecular glues and antibody–drug-conjugate payloads. Intended for medicinal and computational chemists, structural biologists, biophysicists and NMR specialists; prior conformational-design experience is unnecessary. Or

…including targeted degradation and molecular glues, and integrates experimental chemistry with computational and generative design while managing scientific programmes and external partners.

Mariana Kneppers, Neil Withers and Phillip Broadwith discuss molecular glues and efforts to target cancer-related proteins previously considered difficult to drug. They also explore how analysis of fibres and dyes helps researchers investigate and conserve the Bayeux Tapestry.