Topic: motor commands

Navigation requires orienting oneself relative to landmarks in the environment, evaluating relevant sensory data, remembering goals, and convert all this information into motor commands that direct locomotion. I will present models, highly constrained by connectomic, physiological and behavioral data, for how these functions are accomplished in the fly brain.

A fundamental problem in neuroscience is how neuronal activity in the brain generates organized and stable behaviors across multiple timescales. Recent research in many model organisms, e.g. in monkeys, led to the observations that the neuronal encoding of individual actions, such as preparation for and execution of arm movements, is achieved by large neuronal populations but often lies on low-dimensional manifolds. However, it is largely unclear if such manifolds also coordinate higher dimensional activity patterns that correspond to simultaneously executed fine-tuned movements. In order to a