Topic: naltrexone

Rewards are a broad category of stimuli inducing approach behavior to aid survival. Extensive evidence from animal research has shown that wanting (the motivation to pursue a reward) and liking (the pleasure associated with its consumption) are mostly regulated by dopaminergic and opioidergic activity in dedicated brain areas. However, less is known about the neuroanatomy of dopaminergic and opioidergic regulation of reward processing in humans, especially when considering different types of rewards (i.e., social and non-social). To fill this gap of knowledge, we combined dopaminergic and opio

Empathy is a fundamental social-cognitive ability, allowing one to infer about the affective state of another individual and resonate with it, which is crucial for interpersonal relationships. On a neural level, this ability to empathize with others might stem from so-called ‘shared representations’, patterns of neural activation recruited both during the firsthand, as well as the empathic experience of a specific affective state. Correlational evidence for this account using fMRI repeatedly showed overlaps in brain activity for firsthand and witnessed pain. However, despite this correlational