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Topic: network activity

Seminar
2 seminars

In Biology and Computational Neuroscience

Seminar · Computational Neuroscience

An in-silico framework to study the cholinergic modulation of the neocortex

Cristina Colangelo · EPFL, Blue Brain Project

Wed, Jun 30, 2021 · 17:35 UTC

Neuromodulators control information processing in cortical microcircuits by regulating the cellular and synaptic physiology of neurons. Computational models and detailed simulations of neocortical microcircuitry offer a unifying framework to analyze the role of neuromodulators on network activity. In the present study, to get a deeper insight in the organization of the cortical neuropil for modeling purposes, we quantify the fiber length per cortical volume and the density of varicosities for catecholaminergic, serotonergic and cholinergic systems using immunocytochemical staining and stereolo

Seminar · Computational Neuroscience

How single neuron dynamics influence network activity and behaviour

Fleur Zeldenrust · Donders Institute for Brain, Cognition and Behaviour

Wed, Jun 2, 2021 · 17:30 UTC

To understand how the brain can perform complex tasks such as perception, we have to understand how information enters the brain, how it is transformed and how it is transferred. But, how do we measure information transfer in the brain? This presentation will start with a general introduction of what mutual information is and how to measure it in an experimental setup. Next, the talk will focus on how this can be used to develop brain models at different (spatial) levels, from the microscopic single neuron level to the macroscopic network and behavioural level. How can we incorporate the knowl