Network oscillations

…Multiple oscillations have been described in many neural structures of the rodent brain, being commonly associated with various behaviours, computations, and codes, in the sensory, cognitive, and motor domains. The extent to which such oscillatory organisation of neural activity features the human brain remains elusive. To contribute to such an investigation, here we present ongoing cross-species work where we apply the same intra-cranial multi-channel recording technique and analytical framework to cortical and

We often perceive memories as unified experiences although they comprise a multiplicity of different modalities and features. How the different aspects of a memory are encoded separately or jointly in the brain’s memory systems is not well understood. A key brain structure that has been identified to be involved in processing emotional memories is the ventral hippocampus. In our study we use virtual environments to induce in head-fixed mice the recall of distinct memories of a trace fear conditioning, consisting of a cue-triggered temporal and a context-triggered emotional component. To invest

Cortical principal neurons receive multiple synaptic inputs via their dendrites, integrate them in their soma and once a threshold is reached, generate action potentials. Dendritic branches express multiple mechanisms for modulation and integration of signals, depending on the spatiotemporal pattern of arriving inputs. Recently, we have reported a new structural feature of pyramidal neurons affecting neuronal signal processing: axon localization. In about 50% of CA1 hippocampal pyramidal cells, the axon emerges from a basal dendrite instead of the soma. Input to the axon-carrying dendrite (AcD

…mechanisms for neural coordination are network oscillations, which dynamically synchronize neural activity across circuit elements. In MEC, theta and gamma oscill

…pyramidal cells, but coupling to network oscillations is maint

…coupling could account for very fast network oscillations at >80 hz.