Neural activity space

Learning in neural circuits manifests via slow changes in activity driving behaviour changes. Uncovering how the coordination of plasticity mechanisms found in the brain leads to such changes is a difficult problem, chiefly because we do not have access to the synaptic parameters underlying neural computation. Nevertheless, as neural population recording techniques improve and experiments track changes in neural dynamics over long durations, finer details about plastic changes could be inferred by observing and characterizing changes in neural activity. In this work, we present a step towards

…calcium imaging to measure the activity of hippocampal dorsal CA2 pyramidal neurons (dCA2) - a region known for its importance in social memory - in mice interacting with novel and familiar conspecifics in different spatial contexts. Through a dec