Neural connectivity

Tatiana Engel discusses how high-dimensional neural connectivity generates low-dimensional activity associated with cognition. Topics include latent-circuit models, the relationship between manifolds and anatomical networks, brain-wide neuronal timescales and collaborative work through the International Brain Laboratory.

The specific topology of biological neural networks is believed to be one of the most important ingredients of the nervous system's computational capabilities. Furthermore, multiple experimental studies have demonstrated that neural connectivity is highly inhomogeneous, following different patterns between different regions and neuron types. In particular, the presence of clusters of highly interconnected neurons is one of the most well-established connectivity patterns across multiple brain areas. Still, the functional implications of such brain connectivity features, especially for the perfo