Neurodevelopmental conditions

…and are commonly associated with neurodevelopmental conditions such as autism and epilepsy. These conditions often also co-occur and preliminary studies have suggested a convergent aetiology. Thus studying the biological functions of FOXG1 and providing mechanistic insight into its functions can better reveal the molecular and cellular aetiology of these conditions. This will help us accelerate biomarker discovery and therapeutic strategies for epilepsy in individuals with or witho

…the majority of neuropsychiatric and neurodevelopmental conditions. The significance of our social environment makes it even more detrimental if the ability to fully engage with it is impaired. Current methods for analyzing social behavior in neuroscience are often artificial

Behavioural difficulties are seen as hallmarks of many neurodevelopmental conditions. Differences in functional brain organisation have been observed in these conditions, but little is known about how they are related to a child’s profile of behavioural difficulties. We investigated whether behavioural difficulties are associated with how the brain is functionally organised in an intentionally heterogeneous and transdiagnostic sample of 957 children aged 5-15. We used consensus community detection to derive data-driven profiles of behavioural difficulties and constructed functional connectomes