Topic: neurogenesis markers

Adult hippocampal neurogenesis (AHN) gives rise to new neurons throughout life. This phenomenon takes place in more than 120 mammalian species, including humans, yet its occurrence in the latter was questioned after a putative absence of neurogenesis markers in the adult human hippocampus was suggested. In this regard, we showed that prolonged fixation impedes the visualization of Doublecortin+ immature neurons in this structure, whereas a dilated post-mortem delay (PMD) has been suggested to underlie these discrepancies. Nevertheless, the individual and/or additive contribution of fixation an

Naked mole rats are highly vocal eusocial mammals, that rely heavily on vocal communication to form and maintain social groups. We are interested in researching how vocal development genes and neurogenesis markers are expressed in the naked mole rat brain at different developmental timepoints. Here we report preliminary data on immunohistochemical characterization of cortical expression of FOXP2 and Doublecortin in the naked mole rat brain. FOXP2, forkhead-box protein P2, is a transcription factor associated with speech and language. Doublecortin is a neurogenesis marker that shows newly gener