ePoster · Computational Neuroscience
Dual role, single pathway: A pyramidal cell model of feedback integration in function and learning
Daniel Schmid, Christian Jarvers, Timo Oess, Heiko Neumann · Bernstein Conference 2024
Successful integration of feedforward and feedback signals play a major role in cortical processing [1]. Pyramidal cells are thought to be the main sites to perform this integration locally. Signals from the two different pathways are integrated at distinct sites of the pyramidal cell [2]. Information originating up-stream, closer to primary sensory input, is integrated at basal peri-somatic dendrites and drives the cell's firing. Contextual information from down-stream sources is integrated at distal apical dendrites and amplifies the cell's firing only if coinciding with basal input. Importa