Topic: object memory

Neurofibromatosis type I is a monogenetic disorder resulting from a defective copy of the neurofibromin 1 gene. Patients display a complex and varied clinical presentation which may include frequent tumour formation, hyperpigmentation marks, vision disorders and scoliosis. In addition, learning difficulties and psychiatric conditions such as ADHD, autism, anxiety or depression affect the majority of NF1 patients, and these symptom complexes are not addressed by standard therapeutic strategies. Here we employed a mouse model of NF1, the heterozygous Nf1 +/- mouse line. The initial approach invo

Ramelteon is a melatonin receptor agonist utilized to alleviate sleep disorders impacting memory. However, it remains unknown whether ramelteon modulates neutral memories devoid of rewards or punishment. To address this, we observed the behavior of mice during a novel object recognition task and a spontaneous alternation task under vehicle/ramelteon treatment. When ramelteon was administered immediately before training in the novel object recognition task, the object memory was improved, suggesting a specific role of ramelteon in facilitating object recognition memory acquisition. Additionally