Topic: open models

Ming-Yu Liu, NVIDIA vice president of research and head of the Cosmos Lab, joins Practical AI hosts Daniel Whitenack and Chris Benson to discuss AI systems that interact with the physical world. The conversation examines open models, world models and simulation as foundations for robotics and autonomous vehicles, and how research and deployment can advance physical AI. Published 1 October 2026; publisher runtime 47 minutes 19 seconds.

Carnegie Mellon researcher and Abridge co-founder Zachary Lipton discusses where machine learning can help healthcare and why clinical work is harder to automate than software development. The conversation examines medical documentation, decision support, drug discovery, open models and model routing, then turns to academic research, doctoral training and the effects of automation on scientific careers. Hosted by Ravid Shwartz Ziv and Allen Roush. Watch the full conversation on the publisher’s YouTube channel.

John Langford of Microsoft AI Labs discusses whether compact implicit models of the world can improve data efficiency. The conversation examines belief-state compression, Transformer caches, JEPA-style objectives and his Next Latent research. It also covers the value of algorithmic research alongside scaling, agent-assisted experiments, open models, the history of CAPTCHA and the behavior of modern optimizers. Hosted by Ravid Shwartz Ziv and Allen Roush. Watch the full conversation on the publisher’s YouTube channel.

Charles Frye of Modal examines the infrastructure constraints behind large-scale AI research. With Ravid Shwartz Ziv and Allen Roush, he discusses underused hardware, saturated resources, sharing GPU capacity and deciding when to train a model. The conversation also covers inference and speculative decoding, hardware economics, virtualization and the security boundaries around agents and open models. Hosted by Ravid Shwartz Ziv and Allen Roush. Watch the full conversation on the publisher’s YouTube channel.