Topic: Open source hardware

This seminar, hosted by the LIBRE hub project, will provide an in-depth introduction to the Global Open Science Hardware (GOSH) movement. Since its inception, GOSH has been instrumental in advancing open-source hardware within scientific research, fostering a diverse and active community. The seminar will cover the history of GOSH, its current initiatives, and future opportunities, with a particular focus on the contributions and activities of the Latin American branch. This session aims to inform researchers, educators, and policy-makers about the significance and impact of GOSH in promoting

Who says you can't reinvent the wheel?! This running wheel for head-fixed mice allows 3D reconstruction of body kinematics using a single camera and DeepLabCut (or similar) software. A lightweight, transparent polycarbonate floor and a mirror mounted on the inside allow two views to be captured simultaneously. All parts are commercially available or laser cut

The Miniscope Project -- an open-source collaborative effort—was created to accelerate innovation of miniature microscope technology and to increase global access to this technology. Currently, we are working on advancements ranging from optogenetic stimulation and wire-free operation to simultaneous optical and electrophysiological recording. Using these systems, we have uncovered mechanisms underlying temporal memory linking and investigated causes of cognitive deficits in temporal lobe epilepsy. Through innovation and optimization, this work aims to extend the reach of neuroscience research

OpenFlexure is a 3D printed flexure translation stage, developed by a group at the Bath University. The stage is capable of sub-micron-scale motion, with very small drift over time. Which makes it quite good, among other things, for time-lapse protocols that need to be done over days/weeks time, and under space restricted areas, such as fume hoods.

Open-source tools are gaining an increasing foothold in neuroscience. The rising complexity of experiments in systems neuroscience has led to a need for multiple parts of experiments to work together seamlessly. This means that open-source tools that freely interact with each other and can be understood and modified more easily allow scientists to conduct better experiments with less effort than closed tools. Open Ephys is an organization with team members distributed all around the world. Our mission is to advance our understanding of the brain by promoting community ownership of the tools w

FED3 is a device for behavioral training of mice in vivarium home-cages. Mice interact with FED3 through two nose-pokes and FED3 responds with visual stimuli, auditory stimuli, and by dispensing pellets. As it is used in the home-cage FED3 can be used for around-the-clock training of mice over several weeks. FED3 is open-source and can be built by users for ~10-20x less than commercial solutions for training mice. The control code is also open-source and was designed to be easily modified by users.

Modern biological methods often require a large number of experiments to be conducted. For example, dissecting molecular pathways involved in a variety of biological processes in neurons and non-excitable cells requires high-throughput compound library or RNAi screens. Another example requiring large datasets - modern data analysis methods such as deep learning. These have been successfully applied to a number of biological and medical questions. In this talk we will describe an open-source platform allowing such experiments to be automated. The platform consists of an XY stage, perfusion sy

Research tools are paramount for scientific development, they enable researchers to observe and manipulate natural phenomena, learn their principles, make predictions and develop new technologies, treatments and improve living standards. Due to their costs and the geographical distribution of manufacturing companies access to them is not widely available, hindering the pace of research, the ability of many communities to contribute to science and education and reap its benefits. One possible solution for this issue is to create research tools under the open source ethos, where all documentati