Topic: OpenSim

Computational models have been seminal in expanding our understanding of how neural, biomechanical, or physical elements can give rise to behavior. With the forthcoming emergence of nearly complete connectomes of the central nervous system, musculature, and biomechanics of Drosophila, it is only now possible to construct models grounded in anatomy and physiology. Biological experiments, in reciprocity, could complement these models, verifying and enhancing their accuracy. Here, we leverage a biomechanical model of Drosophila to build, for the first time, a Hill-type muscle model using X-ray sc

Individuals with Parkinson's disease (PD) feature reduced walking speed. However, the relationship between walking speed and different task conditions remains unclear. This study aims to investigate walking speed in single and dual-task conditions among individuals with PD. This cross-sectional study analyzes baseline data from a controlled clinical trial developed at “Reference Center for Aging and Movement” (CREM) in Brazil. A total of 15 subjects, 67.1±8.1 years, 9 men, recruited through community advertisements, and diagnosed with PD scoring 1 to 3 on the Hoehn and Yahr (1967) scale. Parti