Seminar · Ophthalmology
Mutation targeted gene therapy approaches to alter rod degeneration and retain cones
Maureen McCall · University of Louisville
Mon, Mar 28, 2022 · 14:00 UTC
My research uses electrophysiological techniques to evaluate normal retinal function, dysfunction caused by blinding retinal diseases and the restoration of function using a variety of therapeutic strategies. We can use our understanding or normal retinal function and disease-related changes to construct optimal therapeutic strategies and evaluate how they ameliorate the effects of disease. Retinitis pigmentosa (RP) is a family of blinding eye diseases caused by photoreceptor degeneration. The absence of the cells that for this primary signal leads to blindness. My interest in RP involves the