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Topic: posterior hippocampus

ePoster
2 ePosters

In Neuroscience

Computational and neuromodulatory mechanisms of impaired trust learning in older adults

Ronald Sladky, Federica Riva, Claus Lamm · FENS Forum 2024

Learning whom to trust is an important social skill, which can be affected by aging and loneliness. An often-used experimental task to study trust learning is the repeated trust game (Berg et al., 1995) where participants repeatedly invest money in another player who can be trustworthy – or not. 50 healthy, neurotypical older adults (64 to 84 years) and 62 younger adults (age: 20 to 33, see Sladky & Riva et al., 2022) played the repeated trust game (Figure 1a) while undergoing 3T functional MRI. We found that trust learning was impaired in older adults, particularly in those who reported h

ePoster · Neuroscience

Direct electrical stimulation of the human amygdala enhances recognition memory for objects but not scenes

Krista Wahlstrom, Justin Campbell, Martina Hollearn, Markus Adamek, James Swift, Lou Blanpain, Tao Xie, Peter Brunner, Stephan Hamann, Amir Arain, Lawrence Eisenman, Joseph Manns, Jon Willie, Cory Inman · FENS Forum 2024

Studies suggest the basolateral amygdala (BLA) modulates memory-consolidation processes via interactions with downstream brain regions like the hippocampus. Furthermore, direct electrical stimulation of the BLA in humans enhances declarative memory, and this memory enhancement is marked by oscillatory interactions between the BLA and hippocampus. However, the BLA disproportionately projects to the anterior hippocampus compared to the posterior hippocampus, regions that process non-spatial information about objects and spatial information about scenes, respectively. Nevertheless, the premise th

ePoster · Neuroscience