364 | Stuart Firestein on How Science Relies on Ignorance and Failure
Sean Carroll's Mindscape
Aug 17, 2026
Stuart Firestein examines why productive science depends on ignorance, unsuccessful experiments and uncertainty as well as established knowledge. The conversation considers research at the boundary of what is understood, the role of conjecture and testing, and the absence of a guaranteed method for making discoveries. It also asks how public understanding and science education can better represent the process of investigation.