Topic: rabies virus-based monosynaptic tracing

After excitotoxic lesions, subsets of striatal astrocytes undergo spontaneous neurogenic activation, leading to the local generation of a large number of neuroblasts for at least six months post-lesion. However, the functional integration of the lesion-induced neurons remains unclear. Fate mapping and 3D reconstruction analyses reveal that striatal neuroblasts undergo a maturation process in which they initially organize in clusters, subsequently disperse as individual cells, and gradually attain complex morphologies, often exhibiting dendritic spines. These neurons fail to express typical mar

Locomotion is an essential and conserved movement that allows humans and animals to interact with their surroundings. Although locomotion appears seemingly effortless, it is an intricate motor behavior that requires the orchestration of several supraspinal and spinal neuronal substrates activating many axial and limb muscles. Thus enabling organisms to navigate through and adapt to their environment. Such context-dependent and episodic locomotor behaviors require an interruption or arrest to adjust the movement toward the aimed goal. However, the neural pathways of motor arrest behaviors upon