Topic: recurrent inhibition

One of the best established recurrent inhibitory pathways is the recurrent inhibition of mammalian motoneurons through Renshaw cells. Golgi cells form an inhibitory feedback circuit in the granular layer of cerebellum. Feedback inhibitory pathways are long established “textbook” elements of neural circuitry, but in both cases their functional role has not been well established. Here I will present some new observations on the function of recurrent inhibition in the spinal-cord, supporting the idea that this connection frequency tunes transmission of inputs through motoneurons. Secondly, I will

Learning in neuronal circuits requires coordinated modifications of synaptic strengths across hierarchical networks to refine computation and improve behavioral outcomes. This coordination requires solving the credit assignment problem. Yet, how neuronal circuits achieve credit assignment remains a central unsolved question in systems neuroscience [1]. Several modeling studies have suggested putative biological mechanisms for back-propagating error signals through multi-layer networks. These functionally motivated models assume distinct neuronal compartments representing local error signals t