REMaST®: A novel immune cell therapy for neural tissue regeneration
Sissi Dolci, Loris Mannino, Alessandra Campanelli, Eros Rossi, Emanuela Bottani, Marzia Di Chio, Francesca Ciambella, Elisa Setten, Stefano Gianoli, Nicola Piazza, Benedetta Savino, Isabel Karkossa, Giuseppe Busetto, Alex Pezzotta, Alessia Amenta, Giulia Pruonto, Alessandra Castagna, Nicola Martinelli, Federico Boschi, Adam Doherty, Maria Teresa Scupoli, Chiara Cavallini, Giorgio Malpeli, Zulkifal Malik, Luana Binaschi, Vincenzo Silani, Marco Sandri, Patrizia Bossolasco, Anna Pistocchi, Marco Endrizzi, Kristin Schubert, Guido Francesco Fumagalli, Massimo Locati, Francesco Bifari, Ilaria Decimo · FENS Forum 2024
Spinal Cord Injury (SCI) is a dramatic and irreversible event that leads to the loss of motor and/or sensory functions. After complete SCI, such as grade ASIA-A lesions, the neural tissue fails to repair causing permanent neurological deficits. Nowadays, complete SCI represents an unmet medical need, with no treatments capable to reduce cell death, heal the neural parenchyma, and promote axonal regrowth. In this work, we have identified a set of tumor-associated macrophages with neurogenic properties opening the prospective for a new effective cell therapy for neural degeneration diseases. We
ePoster · Neuroscience