Topic: Research

Seminar
60 seminars
Grant
40 grants
Conference
28 conferences
Podcast
7 podcasts
Grant

NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

National Institutes of Health
Jan 7, 2028

PA-25-301, posted December 18, 2024 and currently open. NIH's parent announcement for investigator-initiated R01 research project grants not proposing clinical trials; standard NIH submission policies and due dates apply, with the listing closing January 7, 2028.

Conference

21st International Meeting on Chemical Sensors

Concordia University, Montréal, Québec, Canada
Jul 11, 2027

IMCS 2027 convenes the international chemical- and biosensing community at Concordia University to exchange research on chemical sensors, sensing materials, devices, analytical methods, and biological applications.

Conference

2027 Human Genetics and Genomics Conference

University of Southern Maine, Portland, Maine, United States
Jun 27, 2027

The 2027 Gordon Research Conference on Human Genetics and Genomics will convene researchers for intensive discussion of current developments across human genetics and genomic science. The meeting uses the GRC application model, with attendance applications accepted through May 30, 2027 unless the conference becomes oversubscribed earlier.

Conference

OHBM 2027 Annual Meeting

Toronto, Canada
Jun 26, 2027

Annual meeting of the Organization for Human Brain Mapping at the Metro Toronto Convention Centre, bringing together researchers to share groundbreaking research, engage in educational forums, and foster collaboration across neuroimaging methods and applications.

Conference

ISSCR 2027 Annual Meeting

San Francisco, CA, USA
Jun 15, 2027

Annual meeting of the International Society for Stem Cell Research at the Moscone West Convention Center, San Francisco, recognizing 25 years of discovery, collaboration, and progress in stem cell science.

Conference

2027 IEEE International Conference on Robotics and Automation (ICRA)

Seoul, South Korea
May 24, 2027

The flagship conference of the IEEE Robotics and Automation Society, held May 24-28, 2027 at Coex in Seoul, South Korea, bringing together the world's top researchers and industry leaders to advance the field of robotics.

Conference

Comparative (neuro)science in insects

Engelberg, Switzerland
Apr 13, 2027

This EMBO Workshop integrates developmental biology, sensory neuroscience, central circuits, motor control, behavior, population genetics, genomics, and ecology to advance comparative insect neuroscience. Early-career researchers are prioritized for selected talks, and all accepted participants present their work.

Conference

Astrocytes: from molecules to systems

Porto, Portugal
Apr 12, 2027

This EMBO Workshop brings together researchers studying astrocytes from molecular mechanisms to systems-level brain functions. The programme covers astrocyte roles in synapse assembly, circuit modulation, homeostasis, metabolism, memory, behavior, the blood-brain barrier, interactions with neurons and glia, and emerging therapeutic strategies.

Conference

APS Global Physics Summit 2027

Atlanta, GA, USA
Apr 11, 2027

The American Physical Society's Global Physics Summit, the world's largest annual physics research conference, joining the March Meeting and April Meeting; the 2027 edition is announced for April 11-16, 2027 in Atlanta, Georgia.

Conference

AACR Annual Meeting 2027

Orlando, FL, USA
Apr 2, 2027

The American Association for Cancer Research's flagship annual meeting, themed 'Delivering Discovery Science: The Bridge to Breakthrough Therapeutics', at the Orange County Convention Center in Orlando, Florida.

Conference

Marine microbial chemical communication

Den Hoorn, Texel, Netherlands
Mar 15, 2027

This EMBO Workshop brings together researchers studying chemical crosstalk among marine microorganisms, spanning metabolite-mediated ecological interactions, analytical chemistry, microscale fluid dynamics, cell biology and omics-based microbial ecology.

Conference

2027 AAAS Annual Meeting

Hyatt Regency Chicago, Chicago, Illinois
Feb 18, 2027

The multidisciplinary AAAS Annual Meeting convenes scientists, engineers, policymakers, educators, and journalists to examine how research, policy, media, and public trust shape scientific progress and evidence-informed action.

Conference

AAAI-27

Montreal, Canada
Feb 16, 2027

The 41st Annual AAAI Conference on Artificial Intelligence at the Palais des Congres de Montreal, featuring technical papers, special tracks, invited speakers, workshops, tutorials, poster sessions, and competitions to promote AI research and scientific exchange.

Grant

EMBO Postdoctoral Fellowships

EMBO
Jan 22, 2027

Supports internationally mobile postdoctoral researchers in the life sciences for up to two years, including a salary or stipend, a relocation allowance and support for fellows with children. Applications accepted throughout the year; next hard cutoff 22 January 2027, 14:00 CET.

Grant

EMBO Postdoctoral Fellowships

European Molecular Biology Organization
Jan 22, 2027

EMBO Postdoctoral Fellowships support internationally mobile postdoctoral researchers in Europe and around the world for up to two years. The fellowship provides a salary or stipend, relocation support, assistance for fellows with children and access to leadership training and the EMBO fellows network.

Conference

Pacific Symposium on Biocomputing 2027

Fairmont Orchid, Big Island of Hawaii, United States
Jan 3, 2027

The 32nd Pacific Symposium on Biocomputing brings researchers together to present and discuss computational methods applied to biomedical problems, with emphasis on emerging, interdisciplinary areas of biocomputing.

Conference

SICB 2027

Pittsburgh, PA, USA
Jan 3, 2027

Annual meeting of the Society for Integrative and Comparative Biology at the David L. Lawrence Convention Center in Pittsburgh, PA, spanning research across integrative and comparative biology.

Conference

Cell Bio 2026 - An ASCB|EMBO Meeting

San Diego, CA, USA
Dec 12, 2026

Joint ASCB|EMBO meeting at the San Diego Convention Center bringing together the cell biology community to share scientific discoveries, network with colleagues across career stages, and explore new research areas and methodologies.

Conference

NeurIPS 2026

Sydney, Australia; Atlanta, Georgia; Paris, France; and virtual
Dec 6, 2026

The Fortieth Annual Conference on Neural Information Processing Systems brings together interdisciplinary machine-learning research through peer-reviewed sessions, invited talks, demonstrations, tutorials, workshops, and an exposition.

SeminarMolecular Neuroscience

How do Astrocytes Sculpt Synaptic Circuits?

Cagla Eroglu
Columbia University Zuckerman Institute
Dec 1, 2026

Cagla Eroglu presents research on how astrocytes regulate synaptic connectivity during development, function and plasticity. The seminar examines molecular and cellular mechanisms that shape neural circuits using imaging, mouse models and complementary experimental approaches.

Grant

Wellcome Career Development Awards — November 2026 round

Wellcome
Nov 17, 2026

Funding for mid-career researchers from any discipline who have the potential to become international research leaders and whose work relates to human life, health and wellbeing.

Grant

National Science Foundation Translation to Practice (NSF TTP)

U.S. National Science Foundation
Nov 17, 2026

NSF support for translating research discoveries and innovations toward practical use through the TTP Translational and Partnership tracks.

SeminarEngineering

2026 Dresselhaus Lecture

Gang Chen
MIT.nano
Nov 16, 2026

Gang Chen delivers MIT.nano's annual Dresselhaus Lecture, drawing on research that spans electron and phonon transport, thermoelectric energy conversion, microelectronic thermal management, desalination and data-center cooling.

Grant

UKRI Translation: MRC Impact Acceleration Awards

UK Research and Innovation - Medical Research Council
Nov 11, 2026

The Medical Research Council offers single-step support to develop a new or repurposed medicine, medical device, diagnostic, or other medical product. Projects should tackle a high-risk development step backed by prior funding and generate critical data that either de-risks onward progression or supports an evidence-based decision to stop.

Grant

Transformative sustainable AI technologies

UK Research and Innovation
Nov 10, 2026

UK Research and Innovation is funding speculative, high-risk projects that could deliver a step change in the sustainability of future AI systems. Proposals may address energy-efficient algorithms, resource-constrained AI, hardware-software co-design, repairable hardware, and other technology-led advances across the AI stack.

Grant

Wellcome Early-Career Awards – November 2026 round

Wellcome
Nov 10, 2026

Wellcome Early-Career Awards enable researchers to develop an independent research identity through innovative projects that advance understanding of life, health and wellbeing. The November 2026 round is open for applications through the Wellcome Funding platform.

Conference

Knight Initiative - Rosenkranz Aging Symposium

Li Ka Shing Center, Paul Berg Hall, Stanford University, California
Nov 6, 2026

An in-person Stanford symposium highlighting recent progress in brain resilience and aging research, followed by a neuroscience poster session featuring work from the Stanford community.

Grant

NSF SBIR/STTR Pilot Emphasis on Scientific Instrumentation

U.S. National Science Foundation
Nov 4, 2026

NSF funding for startups and small businesses developing next-generation scientific instruments, experimental platforms and enabling technologies for research.

Grant

McKnight Scholar Awards

The McKnight Endowment Fund for Neuroscience
Nov 3, 2026

Supports exceptional young neuroscientists in the early stages of establishing an independent laboratory and research career. Up to ten scholars receive a total award of $225,000 paid in equal installments of $75,000 in 2027, 2028, and 2029; applications open early August 2026.

SeminarNeuroendocrinology

Emily Jacobs - New frontiers in women's brain health

Emily Jacobs
Stanford Wu Tsai Neurosciences Institute
Oct 29, 2026

Emily Jacobs will examine how endocrine transitions such as the circadian cycle, menstrual cycle, pregnancy, and menopause reshape the human brain. The talk combines precision brain imaging with a review of research, policy, and funding efforts intended to close persistent gaps in women's brain-health evidence.

SeminarNeuroscience

The 2026 Picower Lecture with Richard L. Huganir

Richard L. Huganir
The Picower Institute for Learning and Memory at MIT
Oct 28, 2026

Richard L. Huganir discusses research on the molecular mechanisms that regulate glutamate receptors, the brain's major excitatory neurotransmitter receptors, and thereby modulate communication between neurons.

Conference

DNA replication and genome maintenance: from basic biology to human health

EMBL Advanced Training Centre, Heidelberg, Germany and online
Oct 20, 2026

This EMBO-EMBL symposium connects fundamental mechanisms of DNA replication and genome maintenance with human health and disease. Researchers from molecular biology, genetics, chromatin, replication stress and genome stability meet in Heidelberg and online for talks, discussion and scientific exchange.

Conference

ASHG 2026 Annual Meeting

Montreal, QC, Canada
Oct 20, 2026

Annual meeting of the American Society of Human Genetics at the Palais des Congres de Montreal, gathering 7,500+ attendees from 75 countries for 100+ scientific sessions and 240 exhibitors and sponsors across human genetics and genomics research.

Grant

Next generation artificial intelligence: explainable AI

UK Research and Innovation
Oct 20, 2026

UKRI and EPSRC are funding speculative, high-risk fundamental research with the potential to produce a step change in the explainability of future AI systems. The call welcomes work on mechanistic interpretability, output reasoning, process examination, imposed explainability, uncertainty quantification, and novel approaches beyond those examples.

Grant

ERC Starting Grant

European Research Council
Oct 14, 2026

ERC-2027-STG call, opened 22 July 2026. Supports early-career researchers of any nationality to build their own teams and pursue frontier research in any field, with grants of up to EUR 1.5 million for 5 years (additional funding possible for relocation or major costs).

Grant

UKRI Translation: BBSRC Proof of Concept 2026

UK Research and Innovation — Biotechnology and Biological Sciences Research Council
Oct 14, 2026

Funding to translate bioscience research into innovations such as products, services and solutions with real-world economic, societal and environmental impact. Opened 5 August 2026; £3,000,000 total, £100,000–£800,000 per project at 80% full economic cost.

SeminarBiophysics

EMBL Entrepreneurial Minds - Beyond the Structure: My Journey Through Science, Innovation and Life Choices

Ilaria Ferlenghi
EMBL and EMBLEM
Oct 13, 2026

Ilaria Ferlenghi discusses a career spanning structural biology, cryo-electron microscopy, vaccine research and development, and the growing role of artificial intelligence and machine learning in scientific innovation and entrepreneurship.

Conference

The complex life of RNA

EMBL Heidelberg and virtual
Oct 13, 2026

This EMBO and EMBL symposium convenes leaders, postdoctoral researchers, and students to discuss current RNA biology. The programme spans transcription, RNA processing and modification, messenger-RNA export and localisation, RNA surveillance and decay, translation, non-coding RNAs, gene-expression control, and coupling among these processes.

Grant

Engineering Research Initiation (ERI)

U.S. National Science Foundation
Oct 9, 2026

NSF support for new engineering investigators at eligible non-R1 institutions to initiate research programs, build capacity and advance their careers.

Conference

Molecular mechanisms in evolution and ecology

EMBL Heidelberg and virtual
Oct 6, 2026

This EMBO workshop brings experimental and computational researchers together around molecular mechanisms of adaptation, evolutionary dynamics, microbial communities, symbiosis, biodiversity, and cell-environment interactions.

Grant

BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)

National Institutes of Health BRAIN Initiative
Oct 6, 2026

This NIH BRAIN Initiative funding opportunity supports new or substantially advanced theories, mechanistic or predictive models, and computational or statistical methods that improve quantitative understanding of brain function across scales. Tools must address complex neural and behavioral data and be made broadly available to the neuroscience research community.

Grant

BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)

National Institutes of Health BRAIN Initiative
Oct 6, 2026

This NIH BRAIN Initiative opportunity supports dissemination of existing resources into neuroscience research practice. Activities may include distribution of tools and reagents, training in new technologies, access to technology platforms or specialized facilities, minor improvements to resource delivery, and adaptations for user communities.

Grant

Targeted Grants to Institutes

Simons Foundation
Sep 30, 2026

Supports established institutes and research centers in mathematics and the physical sciences to strengthen contacts within the international scientific community; up to $750,000 (inclusive of 20% indirect costs) over a three-year award period, with up to ten grants each year.

Grant

Simons Symposia 2026 call for proposals

Simons Foundation
Sep 30, 2026

The Simons Foundation invites proposals to organize new symposium series in mathematics and theoretical physics, including theoretical computer science. Selected series may comprise up to three weeklong meetings with travel, lodging, and meals covered for participants, creating sustained time for collaboration on timely research problems.

Grant

Postdoctoral Research Fellowships in Biology (PRFB)

U.S. National Science Foundation
Sep 29, 2026

NSF postdoctoral fellowships supporting early-career scientists who combine artificial intelligence with biological research and training to advance biotechnology innovation.

Conference

6th Annual Precision Mental Health Symposium: From Circuits to Mindsets: Precision Mental Health in the Real World

Li Ka Shing Center for Learning and Knowledge, 291 Campus Drive, Stanford, CA 94305
Sep 25, 2026

Stanford's annual Precision Mental Health Symposium explores how neuroscience, psychiatry, data science, and artificial intelligence can translate brain research into real-world mental-health care. Themes include circuits and cognition, biomarkers and neuroimaging, rapid-acting interventions, neuromodulation, and precision therapeutics.

Grant

Pre-doctoral Research Bursary

Cancer Research UK
Sep 24, 2026

Cancer Research UK offers short-term support for clinicians, nurses and allied health professionals to gain early-career cancer-research experience and generate preliminary data before applying for a PhD or MD fellowship.

SeminarReproductive Biology

The Surprising Molecular Changes in Eggs, Sperm, and Females that Mediate Fertility

Mariana Wolfner
NIH Wednesday Afternoon Lecture Series
Sep 23, 2026

Mariana Wolfner presents research on the molecular changes in eggs, sperm, and females that coordinate successful reproduction, drawing on genetic and physiological studies of fertilization. This NIH Wednesday Afternoon Lecture Series event is offered in person and through NIH VideoCast.

SeminarArtificial Intelligence

AI for the Sciences: towards understanding

Klaus Robert Müller
Institute of Science and Technology Austria (ISTA)
Sep 22, 2026

ISTA Lecture by Klaus Robert Müller (TU Berlin & Korea University, Seoul) on how machine learning and AI enable scientific research, particularly in medicine and chemistry, and on explainability techniques for extracting understanding from machine learning models.

SeminarNeuroscience

Lessons from the Dead

Z Yan Wang
Columbia University Zuckerman Institute
Sep 22, 2026

Z Yan Wang presents comparative neuroscience research on the brains and behaviors of octopuses and bumblebees to illuminate life-history processes. The talk is part of Columbia's Tuesdays@10 neuroscience seminar program for researchers across fields and career stages.

Grant

Wellcome Discovery Awards

Wellcome
Sep 22, 2026

Funding for established researchers and teams from any discipline to pursue bold, creative research that can deliver significant shifts in understanding related to human life, health and wellbeing.

Grant

HFSP Accelerator Grant 2027

Human Frontier Science Program
Sep 22, 2026

The HFSP Accelerator Grant helps eligible HFSP Research Grant teams add an independent group leader from an underrepresented eligible country, bringing complementary expertise and strengthening international life-science collaboration.

SeminarSleep Medicine

Early Sleep Biomarkers of Alzheimer's Disease Pathophysiology and Memory Impairment

Bryce Mander
Stanford Center for Sleep and Circadian Sciences
Sep 18, 2026

Bryce Mander presents research on early sleep biomarkers associated with Alzheimer's disease pathophysiology and memory impairment. The William C. Dement Seminar connects sleep and circadian neuroscience with neurodegeneration, cognition and clinically relevant approaches to detecting disease-related change.

SeminarNeuroscience

Deciphering the Dynamics of the Unconscious Brain under General Anesthesia

Emery Brown
Wu Tsai Neurosciences Institute, Stanford University
Sep 17, 2026

Stanford Neurosciences Seminar Series talk by Emery Brown (Massachusetts Institute of Technology, Neuroscience Statistics Research Lab) on deciphering the dynamics of the unconscious brain under general anesthesia, hosted by the Wu Tsai Neurosciences Institute.

Grant

ERC Proof of Concept Grant

European Research Council
Sep 17, 2026

ERC-2026-PoC call funding ERC grantees to explore the innovation potential of their frontier research; a lump sum of EUR 150,000 for a period of 18 months, with one application per Principal Investigator per call.

SeminarComputational Linguistics

SQI Seminar Series: Tal Linzen, NYU

Tal Linzen
MIT Siegel Family Quest for Intelligence
Sep 15, 2026

Tal Linzen, an associate professor of linguistics and data science at New York University and a research scientist at Google, will speak in MIT's Siegel Family Quest for Intelligence seminar series. His work combines behavioral experiments and computational methods to study language learning and comprehension, alongside large-language-model post-training, evaluation, and interpretability.

SeminarCell Biology

Recent advances in organoid production and drug discovery

Hideya Sakaguchi
Sumitomo Bakelite Co., Ltd.
Sep 10, 2026

This English-language webinar examines advances in organoid research, production, and drug discovery. Hideya Sakaguchi covers the developmental-biology origins of neural organoid research and its potential for drug discovery, followed by a keynote from Thomas Mitchell of The Organoid Company and a live question session.

Conference

Cascadia Mucosal Biology Symposium

Allen Institute and University of Washington South Lake Union Campus, Seattle, Washington, United States
Sep 10, 2026

The inaugural Cascadia Mucosal Biology Symposium brings together mucosal biologists and immunologists to discuss mechanistic and translational research on health and disease at mucosal surfaces. Topics include tissue-immune crosstalk, microbial homeostasis, antigen-specific barrier responses, barrier development and repair, and translation to medicine.

Grant

Junior Fellows of the Simons Society of Fellows

Simons Foundation
Sep 10, 2026

The Simons Foundation invites nominations for outstanding early-career scientists to receive up to three years of support for independent research at an educational institution in New York City. Junior Fellows join an interdisciplinary scientific community and participate in weekly lectures and dinners, an annual conference, and a retreat while developing their research programmes.

Grant

NIH Director’s Early Independence Award (DP5 Clinical Trial Optional)

National Institutes of Health
Sep 10, 2026

The NIH Common Fund enables exceptional junior scientists to bypass a traditional postdoctoral period and launch an independent research career at a supportive institution.

SeminarMedicine

Ensuring the Vitality of the Biomedical Research Workforce

Elena Fuentes-Afflick
NIH Wednesday Afternoon Lecture Series
Sep 9, 2026

Elena Fuentes-Afflick examines the state of the biomedical research workforce and the conditions needed to sustain a healthy, productive research enterprise. This NIH Wednesday Afternoon Lecture Series event is offered in person and through NIH VideoCast.

Grant

NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

National Institutes of Health
Sep 9, 2026

RFA-RM-27-001, posted June 29, 2026 and currently open. The Pioneer Award supports individual scientists proposing pioneering, high-impact approaches to major challenges in biomedical or behavioral research; 8 awards expected from $8,000,000 in program funding.

Grant

MSCA Postdoctoral Fellowships 2026

European Commission — Marie Skłodowska-Curie Actions
Sep 9, 2026

HORIZON-MSCA-2026-PF-01 call, open since 9 April 2026 with a budget of EUR 399.05 million expected to fund nearly 1,600 projects. European and Global Postdoctoral Fellowships help researchers acquire new skills through international, interdisciplinary and inter-sectoral mobility.

SeminarNeuroscience

Learning and memory in the infant brain

Nick Turk-Browne
Columbia University Zuckerman Institute
Sep 8, 2026

Nick Turk-Browne presents research using infant functional MRI to investigate how the hippocampus supports learning and memory early in life. The seminar connects neural development, memory formation and infantile amnesia through new methods for studying awake infants.

SeminarBiology

Preparing for non-academic interviews

Anna Swierk
EMBL Fellows' Skills and Career Development
Sep 8, 2026

Industry recruiters and hiring managers share practical advice on preparing for non-academic interviews, followed by a live question-and-answer session for researchers exploring careers beyond academia.

Conference

ECCV 2026

Malmo, Sweden
Sep 8, 2026

The 19th European Conference on Computer Vision, the biennial premier research conference in computer vision and machine learning managed by the European Computer Vision Association, held at Malmo Arena and Malmomassan in Malmo, Sweden.

Conference

Chemical biology 2026

EMBL Heidelberg and virtual
Sep 8, 2026

This EMBO workshop covers emerging chemical-biology research spanning computational protein design, big data and AI, technologies for probing and manipulating biology, chemical synthetic biology, and RNA.

Grant

NIH Director’s Transformative Research Award (R01 Clinical Trial Optional)

NIH Common Fund
Sep 3, 2026

The NIH Common Fund supports individuals or teams pursuing exceptionally innovative, unconventional research with the potential to create or overturn major paradigms across biomedical and behavioral science.

Grant

Project Grants in the Natural and Technical Sciences 2026

Novo Nordisk Foundation
Sep 3, 2026

Supports fundamental research within the natural and technical sciences with potential future applications in life science, health science or sustainability; up to DKK 4 million per project from a DKK 77 million grant capital in 2026. Call opened 19 June 2026.

Grant

ERC Plus Grant 2026

European Research Council
Sep 2, 2026

The ERC Plus Grant supports a single principal investigator pursuing an ambitious, transformative frontier-research project beyond the scope of existing ERC grants, with four to seven years of lump-sum funding.

Grant

Project Grants in Bioscience and Basic Biomedicine

Novo Nordisk Foundation
Sep 1, 2026

Novo Nordisk Foundation open-competition project grants of DKK 1–4.5 million over 1–3 years for fundamental research anchored at a Danish university, hospital or non-profit research institution; call opened 18 June 2026, with an additional DKK 12 million reserved for a strategic theme on microbiota-host interactions.

Grant

ERC Advanced Grant

European Research Council
Aug 27, 2026

ERC-2026-ADG call, opened 28 May 2026. For established researchers with a track-record of significant research achievements, in any scientific field, hosted in an EU Member State or associated country; up to EUR 2.5 million for 5 years, with additional funding possible.

SeminarChronobiology

Wu Tsai Human Performance Alliance Research Symposium

Jamie Zeitzer
Wu Tsai Human Performance Alliance at Stanford
Aug 26, 2026

Stanford's summer research symposium features a keynote by Jamie Zeitzer, undergraduate lightning talks, and a poster and demonstration session on human performance research.

SeminarImmunology

Advancing CAR T Cell Therapy for Brain Tumors: Overcoming Barriers to Efficacy

Christine Brown
Gladstone-UCSF Institute of Genomic Immunology
Aug 25, 2026

Gladstone-UCSF Institute of Genomic Immunology Seminar by Christine Brown, PhD (Deputy Director, T Cell Therapeutics Research Laboratories) on developing and refining redirected CAR T cells for malignant brain tumors, including glioblastoma, tumor heterogeneity, immunosuppressive microenvironments, delivery routes, and manufacturing.

PodcastPodcasts

How to Improve Motivation & Overcome Procrastination | Dr. Masud Husain

Aug 24, 2026

Masud Husain explains the neuroscience of motivation, dopamine, effort, and reward, together with research on apathy, dementia, Parkinson's disease, Alzheimer's disease, and cognitive resilience.

PodcastPsychiatry

Researchers test magic mushrooms as an anorexia treatment

Aug 21, 2026

Scientific American's Science Quickly examines an early pilot trial of psilocybin-assisted therapy for people with long-term anorexia. The episode carefully discusses reported changes in symptoms and motivation, possible neuroplasticity mechanisms, the small uncontrolled sample and the need for larger randomized studies and clinical safeguards.

Grant

NIH Director’s New Innovator Award Program (DP2 Clinical Trial Optional)

National Institutes of Health
Aug 17, 2026

The NIH Common Fund supports exceptionally creative early-stage investigators pursuing bold, high-impact biomedical or behavioral research without requiring preliminary data.

SeminarNeuroscience

Emerging NeuroTech: Ultrasound in Neuroscience

Yaoheng “Mack” Yang
McGovern Institute for Brain Research at MIT
Aug 14, 2026

MIT researchers and students are invited to two talks on emerging applications of ultrasound for non-invasive brain imaging, neural modulation and wearable human-machine interaction.

SeminarNeuroscience

Emerging NeuroTech: Ultrasound in Neuroscience

Massachusetts Institute of Technology
Aug 14, 2026

Two talks present emerging applications of ultrasound technology in neuroscience, spanning brain imaging and human-machine interaction. The in-person seminar is open to MIT researchers, students, and staff and is supported by the MIT School of Science and the Feng Lab at the McGovern Institute.

Grant

Career Awards at the Scientific Interface

Burroughs Wellcome Fund
Aug 14, 2026

CASI provides $560,000 over five years to bridge advanced postdoctoral training and the first years of faculty service for researchers from mathematics, physics, chemistry, computer science, statistics or engineering applying their expertise to biological questions. Pre-proposals due August 14, 2026, 3 pm EDT.

PodcastArtificial Intelligence

Briefing Chat: Anthropic rolls out new AI watermark — will it make a difference?

Aug 14, 2026

Nature staff examine what an invisible watermark for AI-generated text could mean for research integrity and the detection of synthetic content, then discuss cross-cultural research showing that ticklishness is a distinct and specialized body sensation with common anatomical patterns.

SeminarCell Biology

Defining profilin function in mammalian actin dynamics and cell behaviour

Klemens Rottner
Institute of Science and Technology Austria (ISTA)
Aug 13, 2026

Klemens Rottner (Helmholtz Centre for Infection Research, Braunschweig) presents evidence that profilin acts as a master regulator of actin filament dynamics essential for cell migration and growth, controlling both formin- and Arp2/3 complex-dependent actin assembly pathways.

PodcastSynthetic Biology

The probiotic bacteria engineered to treat diabetes

Aug 12, 2026

Nature's podcast explores genetically engineered probiotic bacteria that sense elevated glucose and release therapeutic factors, lowering blood sugar in animal studies. The episode also covers ecological research on pumas, geological erosion, and how a solar eclipse can help researchers probe the Sun's magnetic corona.

PodcastPodcasts

Briefing Chat: Orcas smashed a sunfish to bits — researchers aren’t sure why

Jul 31, 2026

Nature staff discuss a large survey of insect diversity in the Amazon and unusual orca behavior captured on video involving a sunfish.

PodcastNeuroscience

‘Holy grail’ of naked mole-rat research reveals how queens rule

Jul 15, 2026

Nature reporters discuss the chemical signal used by naked mole-rat queens to maintain reproductive hierarchy and how people reason when learning unfamiliar games.

PodcastSignal Processing

Nukes in space? Orbital detector could sniff out warheads

Jul 8, 2026

A Nature Podcast episode examines a compact orbital detector designed to identify hidden nuclear devices and research on threats to Indigenous plant knowledge.

Conference

FENS Forum 2026

Barcelona, Spain
Jul 6, 2026

Europe’s leading neuroscience conference, bringing together researchers, clinicians, and innovators across molecular, cellular, systems, cognitive, and clinical neuroscience.

SeminarNeuroscience

Consciousness at the edge of chaos

Martin Monti
University of California Los Angeles
Dec 13, 2025

Over the last 20 years, neuroimaging and electrophysiology techniques have become central to understanding the mechanisms that accompany loss and recovery of consciousness. Much of this research is performed in the context of healthy individuals with neurotypical brain dynamics. Yet, a true understanding of how consciousness emerges from the joint action of neurons has to account for how severely pathological brains, often showing phenotypes typical of unconsciousness, can nonetheless generate a subjective viewpoint. In this presentation, I will start from the context of Disorders of Consciousness and will discuss recent work aimed at finding generalizable signatures of consciousness that are reliable across a spectrum of brain electrophysiological phenotypes focusing in particular on the notion of edge-of-chaos criticality.

SeminarComputational Neuroscience

Computational Mechanisms of Predictive Processing in Brains and Machines

Dr. Antonino Greco
Hertie Institute for Clinical Brain Research, Germany
Dec 10, 2025

Predictive processing offers a unifying view of neural computation, proposing that brains continuously anticipate sensory input and update internal models based on prediction errors. In this talk, I will present converging evidence for the computational mechanisms underlying this framework across human neuroscience and deep neural networks. I will begin with recent work showing that large-scale distributed prediction-error encoding in the human brain directly predicts how sensory representations reorganize through predictive learning. I will then turn to PredNet, a popular predictive coding inspired deep network that has been widely used to model real-world biological vision systems. Using dynamic stimuli generated with our Spatiotemporal Style Transfer algorithm, we demonstrate that PredNet relies primarily on low-level spatiotemporal structure and remains insensitive to high-level content, revealing limits in its generalization capacity. Finally, I will discuss new recurrent vision models that integrate top-down feedback connections with intrinsic neural variability, uncovering a dual mechanism for robust sensory coding in which neural variability decorrelates unit responses, while top-down feedback stabilizes network dynamics. Together, these results outline how prediction error signaling and top-down feedback pathways shape adaptive sensory processing in biological and artificial systems.

SeminarApplied Mathematics

Computational bio-imaging via inverse scattering

Shwetadwip Chowdhury
Assistant Professor, University of Texas at Austin
Nov 25, 2025

Optical imaging is a major research tool in the basic sciences, and is the only imaging modality that routinely enables non-ionized imaging with subcellular spatial resolutions and high imaging speeds. In biological imaging applications, however, optical imaging is limited by tissue scattering to short imaging depths. This prevents large-scale bio-imaging by allowing visualization of only the outer superficial layers of an organism, or specific components isolated from within the organism and prepared in-vitro.

SeminarInformatics

Introduction to protocols.io: Scientific collaboration through open protocols

Lenny Teytelman
Founder & President of protocols.io
Nov 18, 2025

Research articles and laboratory protocol organization often lack detailed instructions for replicating experiments. protocols.io is an open-access platform where researchers collaboratively create dynamic, interactive, step-by-step protocols that can be executed on mobile devices or the web. Researchers can easily and efficiently share protocols with colleagues, collaborators, the scientific community, or make them public. Real-time communication and interaction keep protocols up to date. Public protocols receive a DOI and enable open communication with authors and researchers to foster efficient experimentation and reproducibility.

SeminarBiophysics

Biomolecular condensates as drivers of neuroinflammation

Steven Boeynaems
Department of Molecular and Human Genetics, Baylor College of Medicine Duncan Neurological Research Institute, Texas Children's Hospital, USA
Nov 4, 2025
SeminarMolecular Biology

NF1 exon 51 alternative splicing: functional implications in Central Nervous System (CNS) Cells

Charoula Peta
Biomedical research Foundation of the Academy of Athens
Oct 22, 2025
SeminarOpen Source

Introduction to protocols.io: Scientific collaboration through open protocols

Lenny Teytelman
Founder & President of protocols.io
Sep 25, 2025

Research articles and laboratory protocol organization often lack detailed instructions for replicating experiments. protocols.io is an open-access platform where researchers collaboratively create dynamic, interactive, step-by-step protocols that can be executed on mobile devices or the web. Researchers can easily and efficiently share protocols with colleagues, collaborators, the scientific community, or make them public. Real-time communication and interaction keep protocols up to date. Public protocols receive a DOI and enable open communication with authors and researchers to foster efficient experimentation and reproducibility.

SeminarBiomedical Engineering

The SIMple microscope: Development of a fibre-based platform for accessible SIM imaging in unconventional environments

Rebecca McClelland
PhD student at the University of Cambridge, United Kingdom.
Aug 26, 2025

Advancements in imaging speed, depth and resolution have made structured illumination microscopy (SIM) an increasingly powerful optical sectioning (OS) and super-resolution (SR) technique, but these developments remain inaccessible to many life science researchers due to the cost, optical complexity and delicacy of these instruments. We address these limitations by redesigning the optical path using in-line fibre components that are compact, lightweight and easily assembled in a “Plug & Play” modality, without compromising imaging performance. They can be integrated into an existing widefield microscope with a minimum of optical components and alignment, making OS-SIM more accessible to researchers with less optics experience. We also demonstrate a complete SR-SIM imaging system with dimensions 300 mm × 300 mm × 450 mm. We propose to enable accessible SIM imaging by utilising its compact, lightweight and robust design to transport it where it is needed, and image in “unconventional” environments where factors such as temperature and biosafety considerations currently limit imaging experiments.

SeminarBrain Imaging

OpenNeuro FitLins GLM: An Accessible, Semi-Automated Pipeline for OpenNeuro Task fMRI Analysis

Michael Demidenko
Stanford University
Aug 1, 2025

In this talk, I will discuss the OpenNeuro Fitlins GLM package and provide an illustration of the analytic workflow. OpenNeuro FitLins GLM is a semi-automated pipeline that reduces barriers to analyzing task-based fMRI data from OpenNeuro's 600+ task datasets. Created for psychology, psychiatry and cognitive neuroscience researchers without extensive computational expertise, this tool automates what is largely a manual process and compilation of in-house scripts for data retrieval, validation, quality control, statistical modeling and reporting that, in some cases, may require weeks of effort. The workflow abides by open-science practices, enhancing reproducibility and incorporates community feedback for model improvement. The pipeline integrates BIDS-compliant datasets and fMRIPrep preprocessed derivatives, and dynamically creates BIDS Statistical Model specifications (with Fitlins) to perform common mass univariate [GLM] analyses. To enhance and standardize reporting, it generates comprehensive reports which includes design matrices, statistical maps and COBIDAS-aligned reporting that is fully reproducible from the model specifications and derivatives. OpenNeuro Fitlins GLM has been tested on over 30 datasets spanning 50+ unique fMRI tasks (e.g., working memory, social processing, emotion regulation, decision-making, motor paradigms), reducing analysis times from weeks to hours when using high-performance computers, thereby enabling researchers to conduct robust single-study, meta- and mega-analyses of task fMRI data with significantly improved accessibility, standardized reporting and reproducibility.

SeminarArtificial Intelligence

A personal journey on understanding intelligence

Li Yang Ku
Google DeepMind
Jul 16, 2025

The focus of this talk is not about my research in AI or Robotics but my own journey on trying to do research and understand intelligence in a rapidly evolving research landscape. I will trace my path from conducting early-stage research during graduate school, to working on practical solutions within a startup environment, and finally to my current role where I participate in more structured research at a major tech company. Through these varied experiences, I will provide different perspectives on research and talk about how my core beliefs on intelligence have changed and sometimes even been compromised. There are no lessons to be learned from my stories, but hopefully they will be entertaining.

SeminarComputer Vision

FLUXSynID: High-Resolution Synthetic Face Generation for Document and Live Capture Images

Raul Ismayilov
University of Twente
Jul 2, 2025

Synthetic face datasets are increasingly used to overcome the limitations of real-world biometric data, including privacy concerns, demographic imbalance, and high collection costs. However, many existing methods lack fine-grained control over identity attributes and fail to produce paired, identity-consistent images under structured capture conditions. In this talk, I will present FLUXSynID, a framework for generating high-resolution synthetic face datasets with user-defined identity attribute distributions and paired document-style and trusted live capture images. The dataset generated using FLUXSynID shows improved alignment with real-world identity distributions and greater diversity compared to prior work. I will also discuss how FLUXSynID’s dataset and generation tools can support research in face recognition and morphing attack detection (MAD), enhancing model robustness in both academic and practical applications.

SeminarComputational Neuroscience

“Brain theory, what is it or what should it be?”

Prof. Guenther Palm
University of Ulm
Jun 27, 2025

n the neurosciences the need for some 'overarching' theory is sometimes expressed, but it is not always obvious what is meant by this. One can perhaps agree that in modern science observation and experimentation is normally complemented by 'theory', i.e. the development of theoretical concepts that help guiding and evaluating experiments and measurements. A deeper discussion of 'brain theory' will require the clarification of some further distictions, in particular: theory vs. model and brain research (and its theory) vs. neuroscience. Other questions are: Does a theory require mathematics? Or even differential equations? Today it is often taken for granted that the whole universe including everything in it, for example humans, animals, and plants, can be adequately treated by physics and therefore theoretical physics is the overarching theory. Even if this is the case, it has turned out that in some particular parts of physics (the historical example is thermodynamics) it may be useful to simplify the theory by introducing additional theoretical concepts that can in principle be 'reduced' to more complex descriptions on the 'microscopic' level of basic physical particals and forces. In this sense, brain theory may be regarded as part of theoretical neuroscience, which is inside biophysics and therefore inside physics, or theoretical physics. Still, in neuroscience and brain research, additional concepts are typically used to describe results and help guiding experimentation that are 'outside' physics, beginning with neurons and synapses, names of brain parts and areas, up to concepts like 'learning', 'motivation', 'attention'. Certainly, we do not yet have one theory that includes all these concepts. So 'brain theory' is still in a 'pre-newtonian' state. However, it may still be useful to understand in general the relations between a larger theory and its 'parts', or between microscopic and macroscopic theories, or between theories at different 'levels' of description. This is what I plan to do.

SeminarBrain Imaging

Functional Imaging of the Human Brain: A Window into the Organization of the Human Mind

Nancy Kanwisher
Massachusetts Institute of Technology & McGovern Institute for Brain Research
Jun 26, 2025
SeminarMolecular Biology

Gene regulation networks in nervous system cancers: identification of novel drug targets

Politis Panagiotis
Center for Basic Research, Biomedical Research Foundation of the Academy of Athens
Jun 20, 2025
SeminarElectrophysiology

An Ecological and Objective Neural Marker of Implicit Unfamiliar Identity Recognition

Tram Nguyen
University of Malta
Jun 11, 2025

We developed a novel paradigm measuring implicit identity recognition using Fast Periodic Visual Stimulation (FPVS) with EEG among 16 students and 12 police officers with normal face processing abilities. Participants' neural responses to a 1-Hz tagged oddball identity embedded within a 6-Hz image stream revealed implicit recognition with high-quality mugshots but not CCTV-like images, suggesting optimal resolution requirements. Our findings extend previous research by demonstrating that even unfamiliar identities can elicit robust neural recognition signatures through brief, repeated passive exposure. This approach offers potential for objective validation of face processing abilities in forensic applications, including assessment of facial examiners, Super-Recognisers, and eyewitnesses, potentially overcoming limitations of traditional behavioral assessment methods.

SeminarBiomedical Engineering

Open Hardware Microfluidics

Vittorio Saggiomo
Associate Professor, Laboratory of BioNanoTechnology, Wageningen University, The Netherlands
Jun 6, 2025

What’s the point of having scientific and technological innovations when only a few can benefit from them? How can we make science more inclusive? Those questions are always in the back of my mind when we perform research in our laboratory, and we have a strong focus on the scientific accessibility of our developed methods from microfabrication to sensor development.

SeminarNeuroscience

Astrocytes release glutamate by regulated exocytosis in health and disease

Vladimir Parpura
Distinguished Professor Zhejiang Chinese Medical University and Director of the International Translational Neuroscience Research Institute, Hangzhou, P.R. China
Jun 5, 2025

Astrocytes release glutamate by regulated exocytosis in health and disease Vladimir Parpura, International Translational Neuroscience Research Institute, Zhejiang Chinese Medical University, Hangzhou, P.R. China Parpura will present you with the evidence that astrocytes, a subtype of glial cells in the brain, can exocytotically release the neurotransmitter glutamate and how this release is regulated. Spatiotemporal characteristic of vesicular fusion that underlie glutamate release in astrocytes will be discussed. He will also present data on a translational project in which this release pathway can be targeted for the treatment of glioblastoma, the deadliest brain cancer.

SeminarMaterials Science

“A Focus on 3D Printed Lenses: Rapid prototyping, low-cost microscopy and enhanced imaging for the life sciences”

Liam Rooney
University of Glasgow
May 22, 2025

High-quality glass lenses are commonplace in the design of optical instrumentation used across the biosciences. However, research-grade glass lenses are often costly, delicate and, depending on the prescription, can involve intricate and lengthy manufacturing - even more so in bioimaging applications. This seminar will outline 3D printing as a viable low-cost alternative for the manufacture of high-performance optical elements, where I will also discuss the creation of the world’s first fully 3D printed microscope and other implementations of 3D printed lenses. Our 3D printed lenses were generated using consumer-grade 3D printers and pose a 225x materials cost-saving compared to glass optics. Moreover, they can be produced in any lab or home environment and offer great potential for education and outreach. Following performance validation, our 3D printed optics were implemented in the production of a fully 3D printed microscope and demonstrated in histological imaging applications. We also applied low-cost fabrication methods to exotic lens geometries to enhance resolution and contrast across spatial scales and reveal new biological structures. Across these applications, our findings showed that 3D printed lenses are a viable substitute for commercial glass lenses, with the advantage of being relatively low-cost, accessible, and suitable for use in optical instruments. Combining 3D printed lenses with open-source 3D printed microscope chassis designs opens the doors for low-cost applications for rapid prototyping, low-resource field diagnostics, and the creation of cheap educational tools.

SeminarNeuroscience

SSFN Webinar - Pain research

Patrik Ernfors
Karolinska Institute
May 14, 2025
SeminarNeuro-Informatics

Harnessing Big Data in Neuroscience: From Mapping Brain Connectivity to Predicting Traumatic Brain Injury

Franco Pestilli
University of Texas, Austin, USA
May 13, 2025

Neuroscience is experiencing unprecedented growth in dataset size both within individual brains and across populations. Large-scale, multimodal datasets are transforming our understanding of brain structure and function, creating opportunities to address previously unexplored questions. However, managing this increasing data volume requires new training and technology approaches. Modern data technologies are reshaping neuroscience by enabling researchers to tackle complex questions within a Ph.D. or postdoctoral timeframe. I will discuss cloud-based platforms such as brainlife.io, that provide scalable, reproducible, and accessible computational infrastructure. Modern data technology can democratize neuroscience, accelerate discovery and foster scientific transparency and collaboration. Concrete examples will illustrate how these technologies can be applied to mapping brain connectivity, studying human learning and development, and developing predictive models for traumatic brain injury (TBI). By integrating cloud computing and scalable data-sharing frameworks, neuroscience can become more impactful, inclusive, and data-driven..

SeminarOpen Source

Recent views on pre-registration

Andy Jahn
University of Michigan
May 2, 2025

A discussion on some recent perspectives on pre-registration, which has become a growing trend in the past few years. This is not just limited to neuroimaging, and it applies to most scientific fields. We will start with this overview editorial by Simmons et al. (2021): https://faculty.wharton.upenn.edu/wp-content/uploads/2016/11/34-Simmons-Nelson-Simonsohn-2021a.pdf, and also talk about a more critical perspective by Pham & Oh (2021): https://www.researchgate.net/profile/Michel-Pham/publication/349545600_Preregistration_Is_Neither_Sufficient_nor_Necessary_for_Good_Science/links/60fb311e2bf3553b29096aa7/Preregistration-Is-Neither-Sufficient-nor-Necessary-for-Good-Science.pdf. I would like us to discuss the pros and cons of pre-registration, and if we have time, I may do a demonstration of how to perform a pre-registration through the Open Science Framework.

SeminarNeuroscienceRecording

Fear learning induces synaptic potentiation between engram neurons in the rat lateral amygdala

Kenneth Hayworth
Carboncopies Foundation & BPF Aspirational Neuroscience
Apr 22, 2025

Fear learning induces synaptic potentiation between engram neurons in the rat lateral amygdala. This study by Marios Abatis et al. demonstrates how fear conditioning strengthens synaptic connections between engram cells in the lateral amygdala, revealed through optogenetic identification of neuronal ensembles and electrophysiological measurements. The work provides crucial insights into memory formation mechanisms at the synaptic level, with implications for understanding anxiety disorders and developing targeted interventions. Presented by Dr. Kenneth Hayworth, this journal club will explore the paper's methodology linking engram cell reactivation with synaptic plasticity measurements, and discuss implications for memory decoding research.

SeminarElectrophysiology

Deepfake emotional expressions trigger the uncanny valley brain response, even when they are not recognised as fake

Casey Becker
University of Pittsburgh
Apr 16, 2025

Facial expressions are inherently dynamic, and our visual system is sensitive to subtle changes in their temporal sequence. However, researchers often use dynamic morphs of photographs—simplified, linear representations of motion—to study the neural correlates of dynamic face perception. To explore the brain's sensitivity to natural facial motion, we constructed a novel dynamic face database using generative neural networks, trained on a verified set of video-recorded emotional expressions. The resulting deepfakes, consciously indistinguishable from videos, enabled us to separate biological motion from photorealistic form. Results showed that conventional dynamic morphs elicit distinct responses in the brain compared to videos and photos, suggesting they violate expectations (n400) and have reduced social salience (late positive potential). This suggests that dynamic morphs misrepresent facial dynamism, resulting in misleading insights about the neural and behavioural correlates of face perception. Deepfakes and videos elicited largely similar neural responses, suggesting they could be used as a proxy for real faces in vision research, where video recordings cannot be experimentally manipulated. And yet, despite being consciously undetectable as fake, deepfakes elicited an expectation violation response in the brain. This points to a neural sensitivity to naturalistic facial motion, beyond conscious awareness. Despite some differences in neural responses, the realism and manipulability of deepfakes make them a valuable asset for research where videos are unfeasible. Using these stimuli, we proposed a novel marker for the conscious perception of naturalistic facial motion – Frontal delta activity – which was elevated for videos and deepfakes, but not for photos or dynamic morphs.

SeminarMedicine

Neurosurgery & Consciousness: Bridging Science and Philosophy in the Age of AI

Isaakidis Dimitrios
Mediterranean Hospital of Cyprus
Apr 11, 2025

Overview of neurosurgery specialty interplay between neurology, psychiatry and neurosurgery. Discussion on benefits and disadvantages of classifications. Presentation of sub-specialties: trauma, oncology, functional, pediatric, vascular and spine. How does an ordinary day of a neurosurgeon look like; outpatient clinic, emergencies, pre/intra/post operative patient care. An ordinary operation. Myth-busting and practical insights of every day practice. An ordinary operation. Hint for research on clinical problems to be solved. The coming ethical frontiers of neuroprosthetics. In part two we will explore the explanatory gap and its significance. We will review the more than 200 theories of the hard problem of consciousness, from the prevailing to the unconventional. Finally, we are going to reflect on the AI advancements and the claims of LLMs becoming conscious

SeminarNeuroscienceRecording

Memory Decoding Journal Club: Reconstructing a new hippocampal engram for systems reconsolidation and remote memory updating

Randal A. Koene
Co-Founder and Chief Science Officer, Carboncopies
Apr 8, 2025

Join us for the Memory Decoding Journal Club, a collaboration between the Carboncopies Foundation and BPF Aspirational Neuroscience. This month, we're diving into a groundbreaking paper: 'Reconstructing a new hippocampal engram for systems reconsolidation and remote memory updating' by Bo Lei, Bilin Kang, Yuejun Hao, Haoyu Yang, Zihan Zhong, Zihan Zhai, and Yi Zhong from Tsinghua University, Beijing Academy of Artificial Intelligence, IDG/McGovern Institute of Brain Research, and Peking Union Medical College. Dr. Randal Koene will guide us through an engaging discussion on these exciting findings and their implications for neuroscience and memory research.

SeminarPharmacology

Decoding ketamine: Neurobiological mechanisms underlying its rapid antidepressant efficacy

Zanos Panos
Translational Neuropharmacology Lab, University of Cyprus, Center for Applied Neurosience & Department of Psychology, Nicosia, Cyprus
Apr 4, 2025

Unlike traditional monoamine-based antidepressants that require weeks to exert effects, ketamine alleviates depression within hours, though its clinical use is limited by side effects. While ketamine was initially thought to work primarily through NMDA receptor (NMDAR) inhibition, our research reveals a more complex mechanism. We demonstrate that NMDAR inhibition alone cannot explain ketamine's sustained antidepressant effects, as other NMDAR antagonists like MK-801 lack similar efficacy. Instead, the (2R,6R)-hydroxynorketamine (HNK) metabolite appears critical, exhibiting antidepressant effects without ketamine's side effects. Paradoxically, our findings suggest an inverted U-shaped dose-response relationship where excessive NMDAR inhibition may actually impede antidepressant efficacy, while some level of NMDAR activation is necessary. The antidepressant actions of ketamine and (2R,6R)-HNK require AMPA receptor activation, leading to synaptic potentiation and upregulation of AMPA receptor subunits GluA1 and GluA2. Furthermore, NMDAR subunit GluN2A appears necessary and possibly sufficient for these effects. This research establishes NMDAR-GluN2A activation as a common downstream effector for rapid-acting antidepressants, regardless of their initial targets, offering promising directions for developing next-generation antidepressants with improved efficacy and reduced side effects.

SeminarNeuroscience

SSFN Webinar - Hearing Research

Anders Fridberger
Linköping University
Mar 28, 2025
Conference

COSYNE 2025

Montreal, Canada
Mar 27, 2025

The COSYNE 2025 conference was held in Montreal with post-conference workshops in Mont-Tremblant, continuing to provide a premier forum for computational and systems neuroscience. Attendees exchanged cutting-edge research in a single-track main meeting and in-depth specialized workshops, reflecting Cosyne’s mission to understand how neural systems function.

SeminarPharmacology

Pharmacological exploitation of neurotrophins and their receptors to develop novel therapeutic approaches against neurodegenerative diseases and brain trauma

Ioannis Charalampopoulos
Professor of Pharmacology, Medical School, University of Crete & Affiliated Researcher, Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology Hellas (FORTH)
Mar 7, 2025

Neurotrophins (NGF, BDNF, NT-3) are endogenous growth factors that exert neuroprotective effects by preventing neuronal death and promoting neurogenesis. They act by binding to their respective high-affinity, pro-survival receptors TrkA, TrkB or TrkC, as well as to p75NTR death receptor. While these molecules have been shown to significantly slow or prevent neurodegeneration, their reduced bioavailability and inability to penetrate the blood-brain-barrier limit their use as potential therapeutics. To bypass these limitations, our research team has developed and patented small-sized, lipophilic compounds which selectively resemble neurotrophins’ effects, presenting preferable pharmacological properties and promoting neuroprotection and repair against neurodegeneration. In addition, the combination of these molecules with 3D cultured human neuronal cells, and their targeted delivery in the brain ventricles through soft robotic systems, could offer novel therapeutic approaches against neurodegenerative diseases and brain trauma.

SeminarBiochemistry

PhenoSign - Molecular Dynamic Insights

Andreas Häberli
PhenoSign
Feb 26, 2025

Do You Know Your Blood Glucose Level? You Probably Should! A single measurement is not enough to truly understand your metabolic health. Blood glucose levels fluctuate dynamically, and meaningful insights require continuous monitoring over time. But glucose is just one example. Many other molecular concentrations in the body are not static. Their variations are influenced by individual physiology and overall health. PhenoSign, a Swiss MedTech startup, is on a mission to become the leader in real-time molecular analysis of complex fluids, supporting clinical decision-making and life sciences applications. By providing real-time, in-situ molecular insights, we aim to advance medicine and transform life sciences research. This talk will provide an overview of PhenoSign’s journey since its inception in 2022—our achievements, challenges, and the strategic roadmap we are executing to shape the future of real-time molecular diagnostics.

SeminarComputational NeuroscienceRecording

Brain Emulation Challenge Workshop

Janne K. Lappalainen
University of Tübingen and Max Planck Research School for Intelligent Systems
Feb 21, 2025

Brain Emulation Challenge workshop will tackle cutting-edge topics such as ground-truthing for validation, leveraging artificial datasets generated from virtual brain tissue, and the transformative potential of virtual brain platforms, such as applied to the forthcoming Brain Emulation Challenge.

SeminarNeuroscience

LRRK2 – a master regulator of neurodegeneration: acting on multiple systems including neuroinflammatory signaling, vesicular trafficking, and cell death pathways

Hardy Rideout
Biomedical Research Foundation, Academy of Athens
Feb 21, 2025
SeminarBrain Imaging

Structural & Functional Neuroplasticity in Children with Hemiplegia

Christos Papadelis
University of Texas at Arlington
Feb 21, 2025

About 30% of children with cerebral palsy have congenital hemiplegia, resulting from periventricular white matter injury, which impairs the use of one hand and disrupts bimanual co-ordination. Congenital hemiplegia has a profound effect on each child's life and, thus, is of great importance to the public health. Changes in brain organization (neuroplasticity) often occur following periventricular white matter injury. These changes vary widely depending on the timing, location, and extent of the injury, as well as the functional system involved. Currently, we have limited knowledge of neuroplasticity in children with congenital hemiplegia. As a result, we provide rehabilitation treatment to these children almost blindly based exclusively on behavioral data. In this talk, I will present recent research evidence of my team on understanding neuroplasticity in children with congenital hemiplegia by using a multimodal neuroimaging approach that combines data from structural and functional neuroimaging methods. I will further present preliminary data regarding functional improvements of upper extremities motor and sensory functions as a result of rehabilitation with a robotic system that involves active participation of the child in a video-game setup. Our research is essential for the development of novel or improved neurological rehabilitation strategies for children with congenital hemiplegia.

SeminarPsychology

Digital Minds: Brain Development in the Age of Technology

Eva Telzer
Winston National Center on Technology Use, Brain and Psychological Development
Feb 17, 2025

Digital Minds: Brain Development in the Age of Technology examines how our increasingly connected world shapes mental and cognitive health. From screen time and social media to virtual interactions, this seminar delves into the latest research on how technology influences brain development, relationships, and emotional well-being. Join us to explore strategies for harnessing technology's benefits while mitigating its potential challenges, empowering you to thrive in a digital age.

SeminarNeuroscience

Vision for perception versus vision for action: dissociable contributions of visual sensory drives from primary visual cortex and superior colliculus neurons to orienting behaviors

Prof. Dr. Ziad M. Hafed
Werner Reichardt Center for Integrative Neuroscience, and Hertie Institute for Clinical Brain Research University of Tübingen
Feb 12, 2025

The primary visual cortex (V1) directly projects to the superior colliculus (SC) and is believed to provide sensory drive for eye movements. Consistent with this, a majority of saccade-related SC neurons also exhibit short-latency, stimulus-driven visual responses, which are additionally feature-tuned. However, direct neurophysiological comparisons of the visual response properties of the two anatomically-connected brain areas are surprisingly lacking, especially with respect to active looking behaviors. I will describe a series of experiments characterizing visual response properties in primate V1 and SC neurons, exploring feature dimensions like visual field location, spatial frequency, orientation, contrast, and luminance polarity. The results suggest a substantial, qualitative reformatting of SC visual responses when compared to V1. For example, SC visual response latencies are actively delayed, independent of individual neuron tuning preferences, as a function of increasing spatial frequency, and this phenomenon is directly correlated with saccadic reaction times. Such “coarse-to-fine” rank ordering of SC visual response latencies as a function of spatial frequency is much weaker in V1, suggesting a dissociation of V1 responses from saccade timing. Consistent with this, when we next explored trial-by-trial correlations of individual neurons’ visual response strengths and visual response latencies with saccadic reaction times, we found that most SC neurons exhibited, on a trial-by-trial basis, stronger and earlier visual responses for faster saccadic reaction times. Moreover, these correlations were substantially higher for visual-motor neurons in the intermediate and deep layers than for more superficial visual-only neurons. No such correlations existed systematically in V1. Thus, visual responses in SC and V1 serve fundamentally different roles in active vision: V1 jumpstarts sensing and image analysis, but SC jumpstarts moving. I will finish by demonstrating, using V1 reversible inactivation, that, despite reformatting of signals from V1 to the brainstem, V1 is still a necessary gateway for visually-driven oculomotor responses to occur, even for the most reflexive of eye movement phenomena. This is a fundamental difference from rodent studies demonstrating clear V1-independent processing in afferent visual pathways bypassing the geniculostriate one, and it demonstrates the importance of multi-species comparisons in the study of oculomotor control.

SeminarComputational Neuroscience

Memory formation in hippocampal microcircuit

Andreakos Nikolaos
Visiting Scientist, School of Computer Science, University of Lincoln, Scientific Associate, National and Kapodistrian University of Athens
Feb 7, 2025

The centre of memory is the medial temporal lobe (MTL) and especially the hippocampus. In our research, a more flexible brain-inspired computational microcircuit of the CA1 region of the mammalian hippocampus was upgraded and used to examine how information retrieval could be affected under different conditions. Six models (1-6) were created by modulating different excitatory and inhibitory pathways. The results showed that the increase in the strength of the feedforward excitation was the most effective way to recall memories. In other words, that allows the system to access stored memories more accurately.

SeminarNeuroscience

Brain macrophage transplantation for research and therapy development

Chris Bennett
University of Pennsilvania
Jan 30, 2025
SeminarNeuroscience

Neurobiological Pathways to Tau-dependent Pathology: Perspectives from flies to humans

Papanikolopoulou Katerina
Biomedical Sciences Research Centre "Alexander Fleming
Jan 24, 2025
SeminarNeuroscienceRecording

Dynamics of braille letter perception in blind readers

Santani Teng
Smith-Kettlewell Eye Research Institute
Jan 23, 2025
SeminarCognitionRecording

Rethinking Attention: Dynamic Prioritization

Sarah Shomstein
George Washington University
Jan 7, 2025

Decades of research on understanding the mechanisms of attentional selection have focused on identifying the units (representations) on which attention operates in order to guide prioritized sensory processing. These attentional units fit neatly to accommodate our understanding of how attention is allocated in a top-down, bottom-up, or historical fashion. In this talk, I will focus on attentional phenomena that are not easily accommodated within current theories of attentional selection – the “attentional platypuses,” as they allude to an observation that within biological taxonomies the platypus does not fit into either mammal or bird categories. Similarly, attentional phenomena that do not fit neatly within current attentional models suggest that current models need to be revised. I list a few instances of the ‘attentional platypuses” and then offer a new approach, the Dynamically Weighted Prioritization, stipulating that multiple factors impinge onto the attentional priority map, each with a corresponding weight. The interaction between factors and their corresponding weights determines the current state of the priority map which subsequently constrains/guides attention allocation. I propose that this new approach should be considered as a supplement to existing models of attention, especially those that emphasize categorical organizations.

SeminarGenetic Engineering

Rett syndrome, MECP2 and therapeutic strategies

Rudolf Jaenisch
Whitehead Institute for Biomedical Research and Department of Biology, MIT, Cambridge, USA
Dec 11, 2024

The development of the iPS cell technology has revolutionized our ability to study development and diseases in defined in vitro cell culture systems. The talk will focus on Rett Syndrome and discuss two topics: (i) the use of gene editing as an approach to therapy and (ii) the role of MECP2 in gene expression (i) The mutation of the X-linked MECP2 gene is causative for the disease. In a female patient, every cell has a wt copy that is, however, in 50% of the cells located on the inactive X chromosome. We have used epigenetic gene editing tools to activate the wt MECP2 allele on the inactive X chromosome. (ii) MECP2 is thought to act as repressor of gene expression. I will present data which show that MECP2 binds to Pol II and acts as an activator for thousands of genes. The target genes are significantly enriched for Autism related genes. Our data challenge the established model of MECP2’s role in gene expression and suggest novel therapeutic approaches.

Conference

FENS Forum 2024

Messe Wien Exhibition & Congress Center, Vienna, Austria
Jun 25, 2024

Organised by FENS in partnership with the Austrian Neuroscience Association and the Hungarian Neuroscience Society, the FENS Forum 2024 will take place on 25–29 June 2024 in Vienna, Austria. The FENS Forum is Europe’s largest neuroscience congress, covering all areas of neuroscience from basic to translational research.

Grant

New Ideas - Request for Applications

Simons Foundation Autism Research Initiative

The Simons Foundation Autism Research Initiative supports bold, high-risk, high-reward ideas that could open new directions in autism science. Letters of intent are accepted on a rolling basis, with selected applicants invited to submit a full application for projects lasting up to two years.

Grant

EPSRC standard research grant, Nov 2023: responsive mode

UK Research and Innovation — Engineering and Physical Sciences Research Council

EPSRC's responsive-mode standard research grant, 'Open - no closing date': applications are accepted continuously and batched internally for assessment. No specified upper limit on grant value or project length; EPSRC funds 80% of the full economic cost.

Grant

EPSRC New Investigator Award: applicant-led mode

UK Research and Innovation - Engineering and Physical Sciences Research Council

The Engineering and Physical Sciences Research Council supports early-career researchers making their first application as project lead to develop an independent research vision and establish a research group. Applications can address any EPSRC-remit field, including artificial intelligence, healthcare technologies, engineering, mathematical sciences, physical sciences, clean energy, security, and quantum technologies.

Grant

NSF 26-517: Core Research in Biological Sciences (BIO Core)

National Science Foundation Directorate for Biological Sciences

The National Science Foundation's BIO Core solicitation supports fundamental biological research across scales, including the neural basis of cognition. The new solicitation was posted on 17 August 2026, accepts proposals at any time, anticipates 250 to 300 awards, and replaces earlier core-program guidance in the Directorate for Biological Sciences.

Grant

MRC: research grant: applicant-led

UK Research and Innovation — Medical Research Council

MRC's applicant-led responsive research grant, explicitly 'Open - no closing date': submit when the application is ready. No upper funding limit — the amount should be appropriate to the project — for up to five years, with MRC funding 80% of full economic cost.

Grant

Division of Integrative Organismal Systems Core Programs (IOS)

U.S. National Science Foundation

NSF core-programs solicitation (NSF 24-546) supporting research on integrative organismal biology, including behavioral, developmental, neural and physiological systems. Proposals are accepted anytime, with an estimated $70,000,000 available per fiscal year across ~150 standard or continuing grants.

ePoster

Open-source solutions for research data management in neuroscience collaborations

Reema Gupta, Thomas Wachtler

Bernstein Conference 2024

ePoster

Automated Research Workflows for Pose Estimation

Chris Brozdowski

Neuromatch 5

ePoster

Research Methods in Cognition Studies & Phenomenology - Challenges and Opportunities

Amanda Nelson

Neuromatch 5

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