ePoster · Computational Neuroscience
Modelling rTMS-Induced Metaplasticity Dynamics within Macroscopic Oscillatory Brain Circuits
Kevin Kadak · Neuromatch 5
Wed, Sep 28, 2022
Transcranial Magnetic Stimulation (TMS) offers a non-invasive clinical treatment for intractable neuropsychiatric disorders, including Major Depressive Disorder (MDD). Repetitive TMS (rTMS) involves administering a series of patterned magnetic pulses through the skull to modulate cortical brain activity and induce synaptic plasticity in aberrant neural circuitry. When successful, rTMS results in lasting therapeutic changes that may reflect an amelioration in cognitive symptoms. The salient parameters that comprise rTMS protocols, such as pulse frequency, amplitude, etc., interact to determine