Topic: reward anticipation

The hippocampus creates a cognitive map of the world to optimize predictions and guide behavior, with the dorsal and ventral hippocampus believed to play unique roles in this process. To understand how such representations evolve with learning and are updated with new experience, we used 2-photon calcium imaging to track the same dCA1 or vCA1 neurons across days as mice learned to associate odor stimuli with different outcomes. During reward (sucrose) associative learning, we find that, initially, odor cues elicited robust responses in dCA1, whereas in vCA1 encoding of odor identity was reduce