Topic: self-supervised learning

Much is known about the neural representations of current environmental location and direction within the hippocampal formation, but use of such a “cognitive map” requires the online representation of desired locations and how to get there, and the neural basis for this function has been more elusive. I will discuss how “theta sweeps” of place and grid cell firing encode the current location (at early phases of each theta cycle) while, at later phases, sampling around the forward direction during exploration and indicating the direction to desired locations during goal-directed navigation. I w

Animals exhibit remarkable learning capabilities with little direct supervision. Likewise, self-supervised learning is an emergent paradigm in artificial intelligence, closing the performance gap to supervised learning. In the context of biology, self-supervised learning corresponds to a setting where one sense or specific stimulus may serve as a supervisory signal for another. After learning, the latter can be used to predict the former. On the implementation level, it has been demonstrated that such predictive learning can occur at the single neuron level, in compartmentalized neurons that s

Children learn to build a visual representation of the world from unsupervised exploration and we hypothesize that a key part of this learning ability is the use of self-generated navigational information as a similarity label to drive a learning objective for self-supervised learning. The goal of this work is to exploit navigational information in a visual environment to provide performance in training that exceeds the state-of-the-art self-supervised training. Here, we show that using spatial and temporal information in the pretraining stage of contrastive learning can improve the performan

Automated axon tracing via fully supervised learning requires annotated 3D brain imagery, which necessitates expertise and labor to produce. Reducing the amount of annotated training data needed for supervised algorithms for axon tracing would expedite critical brain research. In this work, we developed and integrated a self-supervised learning (SSL) algorithm trained on large unannotated data volumes into NeuroTrALE (pictured), a custom AI-driven pipeline for automatic annotation and visualization of 3D brain imagery. Our light sheet microscopy dataset consisted of stained Parvalbumin positiv