Topic: sensorimotor restriction

Physical hypoactivity during childhood, due to sedentary lifestyle, extended bed rest or developmental coordination disorders, induces sensorimotor and behavioral disturbances and increases risk of non-communicable diseases in the future. On the other hand, physical activity is widely recognized for its positive impact on health and is necessary for the harmonious maturation of the neuromuscular system. However, whether physical activity can counteract the deleterious effects of sensorimotor restriction (SMR) remains to be demonstrated. This study aimed to assess whether physical activity can

Childhood is a period of construction of the organism, during which interactions with the environment and regular physical activity favour the maturation of the neuronal networks. However, some children exhibit a sensorimotor restriction (SMR) because they are bedridden or they suffer from a neurodevelopmental disorder. In order to better understand the emergence of neuromuscular disorders in these children, a model of SMR has been developed in rats, consisting in hindlimb casting from postnatal day (PND) 1 to PND 28. These animals display a prominent motor phenotype that includes muscle weakn