BMAL1 in the dorsomedial striatum affects alcohol consumption, affective behavior, and motor function sex-specifically in mice
Mahgol Darvishmolla, Richard Courtemanche, Konrad Schottner, Shimon Amir · FENS Forum 2024
Circadian clock gene expression in various midbrain areas plays a central role in the regulation of behavior, including reward-related processes, affective states, and motor functioning. Specifically, recent work has revealed a sex-specific effect of Bmal1 expression in the striatum on voluntary alcohol consumption in mice: suppression in males and augmentation in females. Interestingly, Bmal1 expression in the nucleus accumbens, a striatal subregion known for its role in mediating reward processes, inhibits alcohol consumption in both males and females, thus indicating that other striatal sub
ePoster · Neuroscience