Topic: sharp wave ripple events

Sequential reactivation (replay) of neurons in the hippocampus has been widely observed in sharp wave ripple events (SWRs) during awake and sleep periods, and they are associated with mnemonic processes, such as memory retrieval, consolidation, future planning and decision making. Previous studies have shown that the replay trajectories in the rat hippocampus are rather random, which resemble at least two different types of stochastic process, one corresponding to Brownian diffusion discovered during sleep SWRs and the other Lévy superdiffusion discovered during awake SWRs. The underlying mech

Research into decision-making suggest that the brain contains multiple systems for generating adaptive strategies. The usual explanation is that each strategy is optimized for different environmental conditions. Neurophysiologically, current theories suggest that habitual control requires dorsolateral striatal (DLS) networks, while deliberative control depends on hippocampus (HC) and medial prefrontal cortex (mPFC). Within mPFC, manipulation studies and prior research suggest that prelimbic cortex (PL) contains strategy representations making it especially important for this interaction. To ex