ePoster · Electrophysiology
Electrical synapses between layer 1 interneurons in the medial prefrontal cortex
Elizaveta Vylekzhanina, Luca Habelt, Christian Cameron de Abos y Padilla, Ilka Diester, Philippe Coulon · FENS Forum 2024
The medial Prefrontal Cortex (mPFC) receives and coordinates signals from many brain regions and is an executive hub for the interplay of sensory, limbic, and motor information. Layer 1 (L1) interneurons are essential for signal integration within the mPFC, and they are known to play a role in the maintenance of brain oscillations. However, little is known about the plasticity of electrical synapses (ES) in the L1 of the mPFC. By paired patch-clamp recordings on acute brain slices, we provide novel and conclusive evidence of functional ES between interneurons in L1 of the mPFC. ES in L1 of mPF