Topic: single-unit responses

The mammalian auditory system is remarkably adaptable, allowing animals to flexibly respond to sensory information in dynamic environments. Flexible behaviors, such as perceptual learning, involve the engagement of various neural circuits including top-down regions such as frontal areas. However, how multiple brain areas communicate to support learning is unclear. Here, we investigate how frontal and sensory cortical areas interact to enable flexible behavior. We used high-density silicon probes to record single-unit responses simultaneously from auditory cortex (AC), and a downstream region i

Normative neural network models provide a valuable tool for answering principled ‘why’ questions about neural structure, function, and organisation from an optimization perspective. However, typical approaches often compare models without controlling for differences in architecture, training dataset or model objective. As a result, it is often difficult to make strong conclusions relating variation in model performance to a given characteristic. Here we ask what factors tend to make models predict neural responses most effectively?To investigate this, we explored how hyperparameter choice impa