Sleep disorders

…attention, memory, emotions, and the sleep-wake cycle, and are disrupted in mental disorders, including schizophrenia and autism. However, the underlying mechanisms of pathology are unknown. I will present novel evidence on key organizational principles, structural, and molecular features of thalamocortical networks, as well as critical thalamic pathway interactions that are likely affected in disorders. This data can facilitate modeling typical and abnormal brain function

…preferences in the associated risk of sleep disorders and stress in international students. Methodology: The study was conducted at the University of Jaen, Spain (September-November 2023), with the participation of 185 international students, mean age (23.19±5.47), of whom 70 (37.8%) were female. The Morningness/Eveningness Questionnaire (MEQ), the Epworth Sleepiness Scale (ESS), the Pre-Sleep Arousal Scale (PSAS), and the Student-Life Stress Inventory (SLSI) were used in the study. Re

Ramelteon is a melatonin receptor agonist utilized to alleviate sleep disorders impacting memory. However, it remains unknown whether ramelteon modulates neutral memories devoid of rewards or punishment. To address this, we observed the behavior of mice during a novel object recognition task and a spontaneous alternation task under vehicle/ramelteon treatment. When ramelteon was administered immediately before training in the novel object recognition task, the object memory was improved, suggesting a specific role of ramelteon in facilitating object recognition memory acquisition. Additionally

…epilepsy is the interaction of sleep mechanisms and seizures. Multiple lines of clinical observations suggest a strong, bi-directional relationship between epilepsy and sleep. Epilepsy and sleep disorders are common comorbidities. Seizures occur more commonly in sleep in many types of epilepsy, and in turn, seizures can cause disrupted sleep. Sudden unexplained death in epilepsy (SUDEP) is strongly associated with sleep. The biological mechanisms underlying this relationship between seizures and sleep are poorly understood,

Many patients presenting to neurology either have primary sleep disorders or suffer from sleep comorbidity. Knowledge on the diagnosis, differential diagnostic considerations, and management of these disorders is therefore mandatory for the general neurologist. This comprehensive course may serve to fulfill part of the preparation requirements for trainees seeking to complete the Royal College Examinations in Neurology. This training course is for R4 and R5 residents in Canadian neurology training programs as well as neurologists.