Topic: Sleep onset

Human chronotypes can be defined as the natural preference for specific wake and sleep times. They are a consequence of the circadian clock individual periods. Cortisol is a key mediator for the rhythmic expression of circadian signals in almost all tissues and strictly regulated by the hypothalamic-pituitary-adrenal (HPA) axis. Diseases affecting HPA signaling might therefore have important consequences on chronotype and connected performance.20 patients with autoimmune adrenilitis and 40 control subjects of comparable age (54.53±18.42 vs 48.56±15.5 years) and sex (14f/6m vs 32f/8m) were asse

Slow wave sleep (SWS) is essential for memory consolidation. When endogenous SWS is boosted by so-tES (0.75Hz) applied during sleep, overnight memory consolidation can be enhanced1. The present study explored whether so-tES (0.75Hz), applied immediately after learning and during wake, could enhance overnight memory consolidation and reduce the need for subsequent sleep, compared to an equivalent sham condition. Healthy young adults (18–35 years; n=14) completed cognitive and motor learning tasks in the evening before receiving 15 minutes of active or sham so-tES over task-related brain regions